BTBD14A Antikörper (C-Term)

Produktnummer ABIN953595

Dieses Anti-BTBD14A-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von BTBD14A in WB und EIA. Geeignet für Human.

Kurzübersicht für BTBD14A Antikörper (C-Term) (ABIN953595)

Target: BTBD14A (BTB (POZ) Domain Containing 14A (BTBD14A))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser BTBD14A Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Enzyme Immunoassay (EIA)

Produktdetails anti-BTBD14A Antikörper

Bindungsspezifität: AA 472-502, C-Term

Spezifität: This antibody recognizes Human NACC2 / BTBD14A (C-term).

Aufreinigung: Protein A column, followed by peptide affinity purification

Immunogen: KLH conjugated synthetic peptide between 472-502 amino acids from the C-terminal region of human NACC2 / BTBD14A

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.25 mg/mL

Buffer: PBS containing 0.09 % (W/V) Sodium Azide as preservative

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Details zu BTBD14A

Target: BTBD14A (BTB (POZ) Domain Containing 14A (BTBD14A))

Andere Bezeichnung: NACC2 / BTBD14A

Hintergrund: BTBD14A (BTB/POZ domain-containing protein 14A), also known as BTBD14, is a 587 amino acid protein that contains one BTB/POZ domain. The BTB/POZ domain mediates homomeric and heteromeric POZ-POZ interactions and is common to transcriptional regulators involved in chromatin modeling. In several BTB/POZ containing proteins, including BCL-6 and the promyelocytic leukemia zinc-finger (PLZF) oncoprotein, this domain interacts with the SMRT/N-CoR-mSin3A HDAC complex and is directly involved in repressing and silencing gene transcription. When this domain is deleted, as with the oncogenic PLZF-RAR chimera of promyelocytic leukemias, this transcriptional repression is attenuated. This suggests that BTBD14A may play a role in transcription regulation.Synonyms: BTB/POZ domain-containing protein 14A, Nucleus accumbens-associated protein 2

Molekulargewicht: 62837 Da

Gen-ID: 138151

NCBI Accession: NP_653254

Pathways: Positive Regulation of Response to DNA Damage Stimulus