MUL1 Antikörper (C-Term)

Produktnummer ABIN953547

Produktdetails anti-MUL1 Antikörper

Target: MUL1 (Mitochondrial E3 Ubiquitin Protein Ligase 1 (MUL1))

Bindungsspezifität: AA 279-309, C-Term

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser MUL1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Enzyme Immunoassay (EIA)

Spezifität: This antibody recognizes MUL1 / RNF218 at C-term.

Kreuzreaktivität (Details): Species reactivity (tested):Human

Aufreinigung: Purified through a Protein A column followed by peptide affinity purification

Immunogen: Synthetic peptide - KLH conjugated - corresponding to the C-terminal region (between 279-309aa) of human MUL1 / RNF218

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.25 mg/mL

Buffer: PBS with 0.09 % (W/V) Sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Details zu MUL1

Target: MUL1 (Mitochondrial E3 Ubiquitin Protein Ligase 1 (MUL1))

Andere Bezeichnung: MUL1 / RNF218 (MUL1 Produkte)

Synonyme: C1orf166 antikoerper, GIDE antikoerper, MAPL antikoerper, MULAN antikoerper, RNF218 antikoerper, RP11-401M16.2 antikoerper, mul1 antikoerper, zgc:92166 antikoerper, 0610009K11Rik antikoerper, AV000801 antikoerper, Gide antikoerper, RGD1309944 antikoerper, im:7146383 antikoerper, zgc:165594 antikoerper, mitochondrial E3 ubiquitin protein ligase 1 antikoerper, mitochondrial E3 ubiquitin protein ligase 1 L homeolog antikoerper, mitochondrial E3 ubiquitin protein ligase 1a antikoerper, mitochondrial ubiquitin ligase activator of NFKB 1 antikoerper, mitochondrial E3 ubiquitin protein ligase 1b antikoerper, MUL1 antikoerper, mul1.L antikoerper, mul1a antikoerper, Mul1 antikoerper, mul1b antikoerper

Hintergrund: E3 ubiquitin-protein ligase that plays a role in the control of mitochondrial morphology. Promotes mitochondrial fragmentation and influences mitochondrial localization. Inhibits cell growth. When overexpressed, activates JNK through MAP3K7/TAK1 and induces caspase-dependent apoptosis. E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfer the ubiquitin to targeted substrates.Synonyms: C1orf166, E3 ubiquitin-protein ligase MUL1, GIDE, Growth inhibition and death E3 ligase, MAPL, MULAN, Mitochondrial ubiquitin ligase activator of NFKB 1, Mitochondrial-anchored protein ligase, Putative NF-kappa-B-activating protein 266, RING finger protein 218

Gen-ID: 79594

NCBI Accession: NP_078820

Pathways: Positive Regulation of Endopeptidase Activity