MRGPRX2 Antikörper (C-Term)

Produktnummer ABIN953498

Produktdetails anti-MRGPRX2 Antikörper

Target: MRGPRX2 (G Protein-Coupled Receptor MRGX2 (MRGPRX2))

Bindungsspezifität: AA 286-316, C-Term

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser MRGPRX2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Enzyme Immunoassay (EIA)

Spezifität: This antibody recognizes MRGPRX2 at C-term.

Kreuzreaktivität (Details): Species reactivity (tested):Human

Aufreinigung: Purified through a Protein A column followed by peptide affinity purification

Immunogen: Synthetic peptide - KLH conjugated - corresponding to the C-terminal region (between 286-316aa) of human MRGPRX2.

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.25 mg/mL

Buffer: PBS with 0.09 % (W/V) Sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Details zu MRGPRX2

Target: MRGPRX2 (G Protein-Coupled Receptor MRGX2 (MRGPRX2))

Andere Bezeichnung: MRGPRX2 (MRGPRX2 Produkte)

Hintergrund: MRGPRX2 is the orphan receptor. Probably involved in the function of nociceptive neurons. May regulate nociceptor function and/or development, including the sensation or modulation of pain. Cortistatin-14 seems to be a high potency ligand at this receptor. Cortistatin has several biological functions including roles in sleep regulation locomotor activity, and cortical function. In receptor-expressing cells, cortistatin-stimulated increases in intracellular Ca(2+) but had no effect on basal or forskolin-stimulated cAMP levels, suggesting that this receptor is G(q)-coupled.Synonyms: MRGX2, Mas-related G-protein coupled receptor member X2

Gen-ID: 117194

NCBI Accession: NP_473371