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MPZ Antikörper

Dieses Huhn Polyklonal-Antikörper erkennt spezifisch MPZ in WB, IHC (p) und IF. Er zeigt eine Reaktivität gegenüber Human und Maus.
Produktnummer ABIN953494

Kurzübersicht für MPZ Antikörper (ABIN953494)

Target

Alle MPZ Antikörper anzeigen
MPZ (Myelin Protein Zero (MPZ))

Reaktivität

  • 43
  • 30
  • 24
  • 15
Human, Maus

Wirt

  • 52
  • 9
  • 2
  • 1
Huhn

Klonalität

  • 55
  • 9
Polyklonal

Konjugat

  • 32
  • 5
  • 4
  • 4
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Dieser MPZ Antikörper ist unkonjugiert

Applikation

  • 53
  • 26
  • 23
  • 13
  • 13
  • 10
  • 9
  • 6
  • 4
  • 3
  • 3
  • 2
  • 2
  • 1
Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (IF)
  • Spezifität

    Recognizes P0 Myelin Protein.

    Aufreinigung

    Affinity Chromatography using a peptide column.

    Immunogen

    Two antipeptide antibodies were generated in Chickens against sequences shared between the Mouse (NP_032649) and Human (NP_000521) gene products. Production: After repeated injections, immune eggs were collected, and the IgY fractions were purified from the yolks. These IgY fractions were then affinity-purified using a peptide column, and the concentrations of the eluates adjusted to 0.2 mg/ml. Finally, equal volumes of both of these affinity purified anti-peptide antibodies were mixed, and the preparation was filter-sterilized.

    Isotyp

    Ig Fraction
  • Applikationshinweise

    Optimal working dilution should be determined by the investigator.

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Konzentration

    0.2 mg/mL

    Buffer

    10 mM PBS, pH 7.2 containing 0.02 % Sodium Azide as preservative.

    Konservierungsmittel

    Sodium azide

    Vorsichtsmaßnahmen

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Lagerung

    4 °C

    Informationen zur Lagerung

    Store the antibody undiluted in the dark at 2-8 °C.
  • Target

    MPZ (Myelin Protein Zero (MPZ))

    Andere Bezeichnung

    MPZ

    Hintergrund

    Human Myelin Protein Zero (Po) is a 28,400 dalton protein (258 amino acids) found in myelin of the PNS, but not the CNS. Expressed in myelinating Schwann cells, Po serves as a homophilic adhesion molecule, allowing adjacent laminae of the myelin sheath to undergo compaction. Po is also a marker of a subpopulation of migrating neural crest cells. Mutations of the MPZ gene product in humans is responsible for Charcot-Marie-Tooth type 1B neuropathies (HMSN1B).Synonyms: MPP, Myelin P0 protein, Myelin peripheral protein, Myelin protein zero

    Gen-ID

    4359

    NCBI Accession

    NP_000521
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