MPZ Antikörper
-
- Target Alle MPZ Antikörper anzeigen
- MPZ (Myelin Protein Zero (MPZ))
-
Reaktivität
- Human, Maus
-
Wirt
-
Huhn
-
Klonalität
- Polyklonal
-
Konjugat
- Dieser MPZ Antikörper ist unkonjugiert
-
Applikation
- Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (IF)
- Spezifität
- Recognizes P0 Myelin Protein.
- Aufreinigung
- Affinity Chromatography using a peptide column.
- Immunogen
- Two antipeptide antibodies were generated in Chickens against sequences shared between the Mouse (NP_032649) and Human (NP_000521) gene products. Production: After repeated injections, immune eggs were collected, and the IgY fractions were purified from the yolks. These IgY fractions were then affinity-purified using a peptide column, and the concentrations of the eluates adjusted to 0.2 mg/ml. Finally, equal volumes of both of these affinity purified anti-peptide antibodies were mixed, and the preparation was filter-sterilized.
- Isotyp
- Ig Fraction
- Top Product
- Discover our top product MPZ Primärantikörper
-
-
- Applikationshinweise
- Optimal working dilution should be determined by the investigator.
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
-
- Konzentration
- 0.2 mg/mL
- Buffer
- 10 mM PBS, pH 7.2 containing 0.02 % Sodium Azide as preservative.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- 4 °C
- Informationen zur Lagerung
- Store the antibody undiluted in the dark at 2-8 °C.
-
- Target
- MPZ (Myelin Protein Zero (MPZ))
- Andere Bezeichnung
- MPZ (MPZ Produkte)
- Hintergrund
- Human Myelin Protein Zero (Po) is a 28,400 dalton protein (258 amino acids) found in myelin of the PNS, but not the CNS. Expressed in myelinating Schwann cells, Po serves as a homophilic adhesion molecule, allowing adjacent laminae of the myelin sheath to undergo compaction. Po is also a marker of a subpopulation of migrating neural crest cells. Mutations of the MPZ gene product in humans is responsible for Charcot-Marie-Tooth type 1B neuropathies (HMSN1B).Synonyms: MPP, Myelin P0 protein, Myelin peripheral protein, Myelin protein zero
- Gen-ID
- 4359
- NCBI Accession
- NP_000521
-