MPZ Antikörper

Produktnummer ABIN953494

Dieser Huhn Polyklonal Antikörper erkennt spezifisch MPZ in WB, IHC (p) und IF. Er zeigt eine Reaktivität gegenüber Human und Maus.

Kurzübersicht für MPZ Antikörper (ABIN953494)

Target: MPZ (Myelin Protein Zero (MPZ))

Reaktivität: Human, Maus

Wirt: Huhn

Klonalität: Polyklonal

Konjugat: Dieser MPZ Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (IF)

Produktdetails anti-MPZ Antikörper

Spezifität: Recognizes P0 Myelin Protein.

Aufreinigung: Affinity Chromatography using a peptide column.

Immunogen: Two antipeptide antibodies were generated in Chickens against sequences shared between the Mouse (NP_032649) and Human (NP_000521) gene products. Production: After repeated injections, immune eggs were collected, and the IgY fractions were purified from the yolks. These IgY fractions were then affinity-purified using a peptide column, and the concentrations of the eluates adjusted to 0.2 mg/ml. Finally, equal volumes of both of these affinity purified anti-peptide antibodies were mixed, and the preparation was filter-sterilized.

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 0.2 mg/mL

Buffer: 10 mM PBS, pH 7.2 containing 0.02 % Sodium Azide as preservative.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C

Informationen zur Lagerung: Store the antibody undiluted in the dark at 2-8 °C.

Details zu MPZ

Target: MPZ (Myelin Protein Zero (MPZ))

Andere Bezeichnung: MPZ

Hintergrund: Human Myelin Protein Zero (Po) is a 28,400 dalton protein (258 amino acids) found in myelin of the PNS, but not the CNS. Expressed in myelinating Schwann cells, Po serves as a homophilic adhesion molecule, allowing adjacent laminae of the myelin sheath to undergo compaction. Po is also a marker of a subpopulation of migrating neural crest cells. Mutations of the MPZ gene product in humans is responsible for Charcot-Marie-Tooth type 1B neuropathies (HMSN1B).Synonyms: MPP, Myelin P0 protein, Myelin peripheral protein, Myelin protein zero

Gen-ID: 4359

NCBI Accession: NP_000521