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Melanophilin Antikörper (C-Term)

MLPH Reaktivität: Human WB, IHC (p), EIA Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN953384
  • Target Alle Melanophilin (MLPH) Antikörper anzeigen
    Melanophilin (MLPH)
    Bindungsspezifität
    • 10
    • 8
    • 6
    • 6
    • 2
    • 1
    • 1
    • 1
    AA 540-569, C-Term
    Reaktivität
    • 35
    • 9
    • 3
    • 1
    Human
    Wirt
    • 35
    • 4
    • 1
    Kaninchen
    Klonalität
    • 38
    • 2
    Polyklonal
    Konjugat
    • 18
    • 5
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser Melanophilin Antikörper ist unkonjugiert
    Applikation
    • 30
    • 21
    • 21
    • 6
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)
    Spezifität
    This antibody recognizes Melanophilin / MLPH at C-term.
    Kreuzreaktivität (Details)
    Species reactivity (tested):Human
    Aufreinigung
    Purified through a Protein A column followed by peptide affinity purification
    Immunogen
    Synthetic peptide - KLH conjugated - corresponding to the C-terminal region (between 540-569aa) of human Melanophilin.
    Isotyp
    Ig Fraction
    Top Product
    Discover our top product MLPH Primärantikörper
  • Applikationshinweise
    Optimal working dilution should be determined by the investigator.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    0.25 mg/mL
    Buffer
    PBS with 0.09 % (W/V) Sodium azide
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handhabung
    Avoid repeated freezing and thawing.
    Lagerung
    4 °C/-20 °C
    Informationen zur Lagerung
    Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • Target
    Melanophilin (MLPH)
    Andere Bezeichnung
    Melanophilin (MLPH Produkte)
    Synonyme
    MGC155106 antikoerper, LOC100222096 antikoerper, 2210418F23Rik antikoerper, 5031433I09Rik antikoerper, AW228792 antikoerper, D1Wsu84e antikoerper, Slac-2a antikoerper, l(1)-3Rk antikoerper, l1Rk3 antikoerper, ln antikoerper, SLAC2-A antikoerper, melanophilin antikoerper, MLPH antikoerper, mlph antikoerper, Mlph antikoerper
    Hintergrund
    The MLPH gene encodes a member of the exophilin subfamily of Rab effector proteins, Melanophilin. The protein forms a ternary complex with the small Ras-related GTPase Rab27A in its GTP-bound form and the motor protein myosin Va. A similar protein complex in mouse functions to tether pigment-producing organelles called melanosomes to the actin cytoskeleton in melanocytes, and is required for visible pigmentation in the hair and skin. A mutation in this gene results in Griscelli syndrome type 3, which is characterized by a silver-gray hair color and abnormal pigment distribution in the hair shaft. Several alternatively spliced transcript variants of this gene have been described, but the full-length nature of some of these variants has not been determined.Synonyms: Exophilin-3, Leaden protein, Ln, Mlph, Slac2a, Slp homolog lacking C2 domains a, Synaptotagmin-like protein 2a
    Gen-ID
    79083
    NCBI Accession
    NP_001035932
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