Der Kaninchen Polyklonal anti-MED26 Antikörper (ABIN953373) detektiert spezifisch MED26 in WB und EIA.
Dieser Antikörper reagiert spezifisch mit Proben aus Human.
Optimal working dilution should be determined by the investigator.
Beschränkungen
Nur für Forschungszwecke einsetzbar
Format
Liquid
Konzentration
0.25 mg/mL
Buffer
PBS containing 0.09 % (W/V) Sodium Azide as preservative
Konservierungsmittel
Sodium azide
Vorsichtsmaßnahmen
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handhabung
Avoid repeated freezing and thawing.
Lagerung
4 °C/-20 °C
Informationen zur Lagerung
Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
Target
MED26
(Mediator Complex Subunit 26 (MED26))
Andere Bezeichnung
MED26
Hintergrund
The activation of gene transcription is a multistep process that is triggered by factors that recognize transcriptional enhancer sites in DNA. These factors work with co-activators to direct transcriptional initiation by the RNA polymerase II apparatus. The protein encoded by this gene is a subunit of the CRSP (cofactor required for SP1 activation) complex, which, along with TFIID, is required for efficient activation by SP1. This protein is also a component of other multisubunit complexes e.g. thyroid hormone receptor-(TR-) associated proteins which interact with TR and facilitate TR function on DNA templates in conjunction with initiation factors and cofactors.Synonyms: ARC70, Activator-recruited cofactor 70 kDa component, CRSP complex subunit 7, CRSP7, Cofactor required for Sp1 transcriptional activation subunit 7, Mediator complex 26, Mediator of RNA polymerase II transcription subunit 26, Transcriptional coactivator CRSP70