MED26 Antikörper (Middle Region)

Produktnummer ABIN953373

Dieses Anti-MED26-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von MED26 in WB und EIA. Geeignet für Human.

Kurzübersicht für MED26 Antikörper (Middle Region) (ABIN953373)

Target: MED26 (Mediator Complex Subunit 26 (MED26))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser MED26 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Enzyme Immunoassay (EIA)

Produktdetails anti-MED26 Antikörper

Bindungsspezifität: AA 190-220, Middle Region

Spezifität: This antibody recognizes Human MED26 (Center).

Aufreinigung: Protein A column, followed by peptide affinity purification

Immunogen: KLH conjugated synthetic peptide between 190-220 amino acids from the Central region of human MED26

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.25 mg/mL

Buffer: PBS containing 0.09 % (W/V) Sodium Azide as preservative

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Details zu MED26

Target: MED26 (Mediator Complex Subunit 26 (MED26))

Andere Bezeichnung: MED26

Hintergrund: The activation of gene transcription is a multistep process that is triggered by factors that recognize transcriptional enhancer sites in DNA. These factors work with co-activators to direct transcriptional initiation by the RNA polymerase II apparatus. The protein encoded by this gene is a subunit of the CRSP (cofactor required for SP1 activation) complex, which, along with TFIID, is required for efficient activation by SP1. This protein is also a component of other multisubunit complexes e.g. thyroid hormone receptor-(TR-) associated proteins which interact with TR and facilitate TR function on DNA templates in conjunction with initiation factors and cofactors.Synonyms: ARC70, Activator-recruited cofactor 70 kDa component, CRSP complex subunit 7, CRSP7, Cofactor required for Sp1 transcriptional activation subunit 7, Mediator complex 26, Mediator of RNA polymerase II transcription subunit 26, Transcriptional coactivator CRSP70

Molekulargewicht: 65446 Da

Gen-ID: 9441

NCBI Accession: NP_004822

Pathways: Regulation of Lipid Metabolism by PPARalpha