MED16 Antikörper (Middle Region)
Kurzübersicht für MED16 Antikörper (Middle Region) (ABIN953369)
Target
Alle MED16 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- AA 252-281, Middle Region
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Spezifität
- This antibody recognizes Human MED16 (Center).
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Aufreinigung
- Protein A column, followed by peptide affinity purification
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Immunogen
- KLH conjugated synthetic peptide between 252-281 amino acids from the Central region of human MED16
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Isotyp
- Ig Fraction
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Applikationshinweise
- Optimal working dilution should be determined by the investigator.
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- 0.25 mg/mL
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Buffer
- PBS containing 0.09 % (W/V) Sodium Azide as preservative
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Handhabung
- Avoid repeated freezing and thawing.
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Lagerung
- 4 °C/-20 °C
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Informationen zur Lagerung
- Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- MED16 (Mediator Complex Subunit 16 (MED16))
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Andere Bezeichnung
- MED16
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Hintergrund
- Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.Synonyms: DRIP92, Mediator complex subunit 16, Mediator of RNA polymerase II transcription subunit 16, THRAP5, Thyroid hormone receptor-associated protein complex 95 kDa component, Vitamin D3 receptor-interacting protein complex component DRIP92
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Molekulargewicht
- 72kd
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Gen-ID
- 10025
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NCBI Accession
- NP_005472
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Pathways
- Intracellular Steroid Hormone Receptor Signaling Pathway, Nuclear Hormone Receptor Binding, Regulation of Lipid Metabolism by PPARalpha
Target
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