MECOM Antikörper (Middle Region)

Produktnummer ABIN953364

Dieses Anti-MECOM-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von MECOM in WB und EIA. Geeignet für Human und Maus.

Kurzübersicht für MECOM Antikörper (Middle Region) (ABIN953364)

Target: MECOM (MDS1 and EVI1 Complex Locus (MECOM))

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser MECOM Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Enzyme Immunoassay (EIA)

Produktdetails anti-MECOM Antikörper

Bindungsspezifität: AA 80-109, Middle Region

Spezifität: This antibody recognizes Human and Mouse MDS1 (Center).

Aufreinigung: Protein A column, followed by peptide affinity purification

Immunogen: KLH conjugated synthetic peptide between 80-109 amino acids from the Central region of human MDS1 Genename: MECOM

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.25 mg/mL

Buffer: PBS containing 0.09 % (W/V) Sodium Azide as preservative

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Details zu MECOM

Target: MECOM (MDS1 and EVI1 Complex Locus (MECOM))

Andere Bezeichnung: MDS1

Hintergrund: MDS1 is located at 3q26 170-400 kb upstream (telomeric) of EVI1 in the chromosomal region in which some of the breakpoints 5' of EVI1 have been mapped. MDS1 has been identified as a single gene as well as a previously unreported exon (s) of EVI1. MDS1 exists in normal tissues both as a unique transcript and as a normal fusion transcript with EVI1, with an additional 188 codons at the 5' end of the previously reported EVI1 open reading frame. In cells with translocation t (3,21), additional fusion transcripts are AML1-MDS1 and AML1-MDS1-EVI1. EVI1 and MDS1 are involved in leukemia associated with chromosomal translocation breakpoints in the region between these genes.Synonyms: Myelodysplasia syndrome 1, Myelodysplasia syndrome-associated protein 1

Molekulargewicht: 18696 Da

Gen-ID: 2122

NCBI Accession: NP_004982