Telefon:
+49 (0)241 95 163 153
Fax:
+49 (0)241 95 163 155
E-Mail:
orders@antikoerper-online.de

MAP4K1 Antikörper

MAP4K1 Reaktivität: Human WB, IHC (p), IP Wirt: Maus Monoclonal 2A1 unconjugated
Produktnummer ABIN953299
  • Target Alle MAP4K1 Antikörper anzeigen
    MAP4K1 (Mitogen-Activated Protein Kinase Kinase Kinase Kinase 1 (MAP4K1))
    Reaktivität
    • 61
    • 9
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    Human
    Wirt
    • 57
    • 3
    • 1
    Maus
    Klonalität
    • 59
    • 2
    Monoklonal
    Konjugat
    • 31
    • 4
    • 4
    • 4
    • 4
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser MAP4K1 Antikörper ist unkonjugiert
    Applikation
    • 50
    • 33
    • 15
    • 14
    • 14
    • 14
    • 8
    • 7
    • 4
    • 3
    • 3
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunoprecipitation (IP)
    Spezifität
    Recognizes MAP4K1
    Kreuzreaktivität (Details)
    Species reactivity (tested):Human.
    Aufreinigung
    Ammonium Sulfate Precipitation
    Immunogen
    Recombinant Human protein purified from E. coli (His/ABD-HPK1).
    Klon
    2A1
    Isotyp
    IgG1
    Top Product
    Discover our top product MAP4K1 Primärantikörper
  • Applikationshinweise
    Optimal working dilution should be determined by the investigator.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Buffer
    HEPES with 0.15 M NaCl, 0.01 % BSA, 0.03 % Sdium Azide and 50 % Glycerol
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handhabung
    Avoid repeated freezing and thawing.
    Lagerung
    4 °C/-20 °C
    Informationen zur Lagerung
    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • Target
    MAP4K1 (Mitogen-Activated Protein Kinase Kinase Kinase Kinase 1 (MAP4K1))
    Andere Bezeichnung
    MAP4K1 (MAP4K1 Produkte)
    Synonyme
    HPK1 antikoerper, Hpk1 antikoerper, mHPK1 antikoerper, mitogen activated protein kinase kinase kinase kinase 1 antikoerper, mitogen-activated protein kinase kinase kinase kinase 1 antikoerper, Map4k1 antikoerper, MAP4K1 antikoerper
    Hintergrund
    HPK1, a KHS protein kinase, is an upstream activator of the stress-activated protein kinase (SAPK) signaling pathway. The protein has a structure similar to other GCK (Group I) kinases and contains four consensus SH3 binding motifs, which have been shown to interact with the SH3 motifs of the MAP kinase kinase kinases MLK3 and MEKK1 and several adapter proteins that couple to tyrosine kinases, including BASH, Blnk, Clnk, Crk, CrkL and Grb2. Additionally, HPK1 has been shown to be phosphorylated and activated by the tyrosine kinase c-Abl in response to genotoxic agents. At least two mRNA transcripts have been reported.Synonyms: HPK1, Hematopoietic progenitor kinase, MAPK/ERK kinase kinase kinase 1, MEKKK 1, Mitogen-activated protein kinase kinase kinase kinase 1
    Gen-ID
    11184
    NCBI Accession
    NP_001036065
    UniProt
    Q92918
    Pathways
    T-Zell Rezeptor Signalweg, Signaling of Hepatocyte Growth Factor Receptor
Sie sind hier:
Kundenservice