MXD3 Antikörper (N-Term)

Produktnummer ABIN953278

Produktdetails anti-MXD3 Antikörper

Target: MXD3 (MAX Dimerization Protein 3 (MXD3))

Bindungsspezifität: AA 27-56, N-Term

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser MXD3 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Enzyme Immunoassay (EIA)

Spezifität: This antibody recognizes human MAD3 at N-term.

Aufreinigung: Purified through a Protein A column followed by peptide affinity purification

Immunogen: Synthetic peptide - KLH conjugated - corresponding to the N-terminal region (between 27-56aa) of human MAD3

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.25 mg/mL

Buffer: PBS with 0.09 % (W/V) Sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Details zu MXD3

Target: MXD3 (MAX Dimerization Protein 3 (MXD3))

Andere Bezeichnung: MAD3 (MXD3 Produkte)

Hintergrund: The MXD3 gene encodes a member of the Myc superfamily of basic helix-loop-helix leucine zipper transcriptional regulators. The Max-associated protein 3 / MAD3 forms a heterodimer with the cofactor MAX which binds specific E-box DNA motifs in the promoters of target genes and regulates their transcription. Disruption of the MAX-MXD3 complex is associated with uncontrolled cell proliferation and tumorigenesis. Transcript variants of this gene encoding different isoforms have been described.Synonyms: MAD-3, MXD3, Max-interacting transcriptional repressor MAD3

Molekulargewicht: 23477 Da

Gen-ID: 83463

NCBI Accession: NP_001136407