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Integrin beta 7 Antikörper (C-Term)

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch Integrin beta 7 in WB und EIA. Er zeigt eine Reaktivität gegenüber Human.
Produktnummer ABIN952915

Kurzübersicht für Integrin beta 7 Antikörper (C-Term) (ABIN952915)

Target

Alle Integrin beta 7 (ITGB7) Antikörper anzeigen
Integrin beta 7 (ITGB7)

Reaktivität

  • 77
  • 31
  • 1
  • 1
  • 1
Human

Wirt

  • 50
  • 20
  • 7
  • 4
  • 1
Kaninchen

Klonalität

  • 51
  • 29
  • 2
Polyklonal

Konjugat

  • 36
  • 8
  • 5
  • 4
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Dieser Integrin beta 7 Antikörper ist unkonjugiert

Applikation

  • 40
  • 28
  • 22
  • 13
  • 13
  • 9
  • 8
  • 8
  • 5
  • 4
  • 4
  • 4
  • 3
  • 3
  • 1
  • 1
  • 1
Western Blotting (WB), Enzyme Immunoassay (EIA)
  • Bindungsspezifität

    • 15
    • 9
    • 4
    • 4
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 736-765, C-Term

    Spezifität

    This antibody recognizes Human Integrin beta-7 (C-term).

    Aufreinigung

    Protein A column, followed by peptide affinity purification

    Immunogen

    KLH conjugated synthetic peptide between 736-765 amino acids from the C-terminal region of Human Integrin beta-7

    Isotyp

    Ig Fraction
  • Applikationshinweise

    Optimal working dilution should be determined by the investigator.

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Liquid

    Konzentration

    0.25 mg/mL

    Buffer

    PBS containing 0.09 % (W/V) Sodium Azide as preservative

    Konservierungsmittel

    Sodium azide

    Vorsichtsmaßnahmen

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Handhabung

    Avoid repeated freezing and thawing.

    Lagerung

    4 °C/-20 °C

    Informationen zur Lagerung

    Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • Target

    Integrin beta 7 (ITGB7)

    Andere Bezeichnung

    Integrin beta-7

    Hintergrund

    Integrin alpha-4/beta-7 (Peyer patches-specific homing receptor LPAM-1) is an adhesion molecule that mediates lymphocyte migration and homing to gut-associated lymphoid tissue (GALT). Integrin alpha-4/beta-7 interacts with the cell surface adhesion molecules MADCAM1 which is normally expressed by the vascular endothelium of the gastrointestinal tract. Interacts also with VCAM1 and fibronectin, an extracellular matrix component. It recognizes one or more domains within the alternatively spliced CS-1 region of fibronectin. Interactions involves the tripeptide L-D-T in MADCAM1, and L-D-V in fibronectin. Binds to HIV-1 gp120, thereby allowing the virus to enter GALT, which is thought to be the major trigger of AIDS disease. Interaction would involve a tripeptide L-D-I in HIV-1 gp120. Integrin alpha-E/beta-7 (HML-1) is a receptor for E-cadherin.Synonyms: ITGB7, Integrin alpha 4 beta 7, Integrin beta-P, LPAM-1, LPAM1, M290 IEL antigen

    Molekulargewicht

    86903 Da

    Gen-ID

    3695

    NCBI Accession

    NP_000880

    Pathways

    Integrin Complex
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