HYAL2 Antikörper (Middle Region)

Produktnummer ABIN952808

Der Kaninchen Polyklonal anti-HYAL2 Antikörper wird verwendet zum Nachweis von HYAL2 in Proben von Human. Er wurde validiert für WB, IHC (p) und EIA.

Kurzübersicht für HYAL2 Antikörper (Middle Region) (ABIN952808)

Target: HYAL2 (Hyaluronidase-2 (HYAL2))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser HYAL2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Produktdetails anti-HYAL2 Antikörper

Bindungsspezifität: AA 127-157, Middle Region

Spezifität: This antibody recognizes Human HYAL2 / Hyaluronidase-2 (Center).

Aufreinigung: Protein A column, followed by peptide affinity purification

Immunogen: KLH conjugated synthetic peptide between 127-157 amino acids from the Central region of Human HYAL2 / Hyaluronidase-2.

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.25 mg/mL

Buffer: PBS containing 0.09 % (W/V) Sodium Azide as preservative

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Details zu HYAL2

Target: HYAL2 (Hyaluronidase-2 (HYAL2))

Andere Bezeichnung: HYAL2 / Hyaluronidase-2

Hintergrund: This gene encodes a weak acid-active hyaluronidase. The encoded protein is similar in structure to other more active hyaluronidases. Hyaluronidases degrade hyaluronan, one of the major glycosaminoglycans of the extracellular matrix. Hyaluronan and fragments of hyaluronan are thought to be involved in cell proliferation, migration and differentiation. Although it was previously thought to be a lysosomal hyaluronidase that is active at a pH below 4, the encoded protein is likely a GPI-anchored cell surface protein. This hyaluronidase serves as a receptor for the oncogenic virus Jaagsiekte sheep retrovirus. The gene is one of several related genes in a region of chromosome 3p21.3 associated with tumor suppression. This gene encodes two alternatively spliced transcript variants which differ only in the 5' UTR.Synonyms: Hyal-2, Hyaluronoglucosaminidase-2, LUCA2, Lung carcinoma protein 2

Molekulargewicht: 53860 Da

Gen-ID: 8692

NCBI Accession: NP_003764

Pathways: Transition Metal Ion Homeostasis, Glycosaminoglycan Metabolic Process