HNF1B Antikörper (C-Term)

Produktnummer ABIN952765

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch HNF1B in WB und EIA. Er zeigt eine Reaktivität gegenüber Human.

Kurzübersicht für HNF1B Antikörper (C-Term) (ABIN952765)

Target: HNF1B (HNF1 Homeobox B (HNF1B))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser HNF1B Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Enzyme Immunoassay (EIA)

Produktdetails anti-HNF1B Antikörper

Bindungsspezifität: AA 505-536, C-Term

Spezifität: This antibody recognizes Human HNF1 beta / TCF2 (C-term).

Aufreinigung: Protein A column, followed by peptide affinity purification

Immunogen: KLH conjugated synthetic peptide between 505-536 amino acids from the C-terminal region of human HNF1B

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.25 mg/mL

Buffer: PBS containing 0.09 % (W/V) Sodium Azide as preservative

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Details zu HNF1B

Target: HNF1B (HNF1 Homeobox B (HNF1B))

Andere Bezeichnung: HNF1 beta / TCF2

Hintergrund: This gene encodes a member of the homeodomain-containing superfamily of transcription factors. The protein binds to DNA as either a homodimer, or a heterodimer with the related protein hepatocyte nuclear factor 1-alpha. The gene has been shown to function in nephron development, and regulates development of the embryonic pancreas. Mutations in this gene result in renal cysts and diabetes syndrome and noninsulin-dependent diabetes mellitus, and expression of this gene is altered in some types of cancer. Multiple transcript variants encoding different isoforms have been found for this geneSynonyms: HNF-1-beta, HNF-1B, Hepatocyte nuclear factor 1-beta, LFB3, TCF-2, Transcription factor 2, Variant hepatic nuclear factor 1, vHNF1

Molekulargewicht: 61324 Da

Gen-ID: 6928

NCBI Accession: NP_000449

Pathways: Hormone Transport, Stem Cell Maintenance, Tube Formation