H2AFY2 Antikörper (N-Term)

Produktnummer ABIN952667

Produktdetails anti-H2AFY2 Antikörper

Target: H2AFY2 (H2A Histone Family, Member Y2 (H2AFY2))

Bindungsspezifität: AA 14-43, N-Term

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser H2AFY2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Flow Cytometry (FACS), Enzyme Immunoassay (EIA)

Spezifität: This antibody recognizes Human and Mouse H2AFY2 / MACROH2A2 (N-term).

Aufreinigung: Protein A column, followed by peptide affinity purification

Immunogen: KLH conjugated synthetic peptide between 14-43 amino acids from the N-terminal region of Human H2AFY2 / MACROH2A2

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.25 mg/mL

Buffer: PBS containing 0.09 % (W/V) Sodium Azide as preservative

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Details zu H2AFY2

Target: H2AFY2 (H2A Histone Family, Member Y2 (H2AFY2))

Andere Bezeichnung: H2AFY2 / MACROH2A2 (H2AFY2 Produkte)

Hintergrund: Variant histone H2A which replaces conventional H2A in a subset of nucleosomes where it represses transcription. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. May be involved in stable X chromosome inactivation.Synonyms: Core histone macro-H2A.2, Histone macroH2A2, mH2A2

Molekulargewicht: 40058 Da

Gen-ID: 55506

NCBI Accession: NP_061119