GPR17 Antikörper (Middle Region)

Produktnummer ABIN952606

Produktdetails anti-GPR17 Antikörper

Target: GPR17 (G Protein-Coupled Receptor 17 (GPR17))

Bindungsspezifität: AA 237-266, Middle Region

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser GPR17 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Spezifität: This antibody detects human GPR17.

Kreuzreaktivität (Details): Species reactivity (tested):Human

Aufreinigung: Purified through a protein A column; followed by peptide affinity purification.

Immunogen: Synthetic peptide - KLH conjugated - corresponding to the central region (between 237-266aa) of human GPR17.

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.25 mg/mL

Buffer: PBS with 0.09 % (W/V) Sodium Azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Details zu GPR17

Target: GPR17 (G Protein-Coupled Receptor 17 (GPR17))

Andere Bezeichnung: GPR17 (GPR17 Produkte)

Synonyme: GPR17 antikoerper, AI853548 antikoerper, G protein-coupled receptor 17 antikoerper, GPR17 antikoerper, Gpr17 antikoerper

Hintergrund: Members of the G protein coupled receptor (GPCR) superfamily contain 7 transmembrane domains and transduce extracellular signals through heterotrimeric G proteins. The organization of the GPR17 gene differs from that of many other GPCRs in that the open reading frame is distributed on 2 exons, an additional exon contains the 5 prime untranslated region. Human GPR17 is expressed as 2.3 and 6.3 kb mRNAs exclusively in brain. The 2 transcripts appear to represent alternatively polyadenylated variants. Based on protein sequence homology and the conservation of certain key residues, GPR17 appears to be closely related to the P2Y family of GPCRs. There are two nemed isoforms.Synonyms: G-protein coupled receptor 17, P2Y-like receptor, R12, UDP/CysLT receptor, Uracil nucleotide/cysteinyl leukotriene receptor

Gen-ID: 2840

NCBI Accession: NP_001154887