GLDC Antikörper (N-Term)

Produktnummer ABIN952523

Der Kaninchen Polyklonal Anti-GLDC-Antikörper wurde für WB und EIA validiert. Er ist geeignet, GLDC in Proben von Human und Maus zu detektieren.

Kurzübersicht für GLDC Antikörper (N-Term) (ABIN952523)

Target: GLDC (Glycine Dehydrogenase (GLDC))

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser GLDC Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Enzyme Immunoassay (EIA)

Produktdetails anti-GLDC Antikörper

Bindungsspezifität: AA 56-85, N-Term

Spezifität: This antibody recpognizes Human and Mouse GLDC (N-term).

Aufreinigung: Protein A column, followed by peptide affinity purification

Immunogen: KLH conjugated synthetic peptide between 56~85 amino acids from the N-terminal region of Human GLDC

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.25 mg/mL

Buffer: PBS containing 0.09 % (W/V) Sodium Azide as preservative

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Details zu GLDC

Target: GLDC (Glycine Dehydrogenase (GLDC))

Andere Bezeichnung: GLDC

Hintergrund: Degradation of glycine is brought about by the glycine cleavage system, which is composed of four mitochondrial protein components: P protein (a pyridoxal phosphate-dependent glycine decarboxylase), H protein (a lipoic acid-containing protein), T protein (a tetrahydrofolate-requiring enzyme), and L protein (a lipoamide dehydrogenase). The protein is the P protein, which binds to glycine and enables the methylamine group from glycine to be transferred to the T protein. Defects in this gene are a cause of nonketotic hyperglycinemia (NKH).Synonyms: GCSP, Glycine cleavage system P protein, Glycine decarboxylase, Glycine dehydrogenase [decarboxylating], mitochondrial

Molekulargewicht: 112730 Da

Gen-ID: 2731

NCBI Accession: NP_000161