GALNT4 Antikörper (N-Term)

Produktnummer ABIN952445

Der Kaninchen Polyklonal anti-GALNT4 Antikörper wird verwendet zum Nachweis von GALNT4 in Proben von Human. Er wurde validiert für WB, FACS und EIA.

Kurzübersicht für GALNT4 Antikörper (N-Term) (ABIN952445)

Target: GALNT4 (UDP-N-Acetyl-alpha-D-Galactosamine:polypeptide N-Acetylgalactosaminyltransferase 4 (GalNAc-T4) (GALNT4))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser GALNT4 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Flow Cytometry (FACS), Enzyme Immunoassay (EIA)

Produktdetails anti-GALNT4 Antikörper

Bindungsspezifität: AA 100-128, N-Term

Spezifität: This antibody recognizes Human GALNT4 (N-term).

Aufreinigung: Protein A column, followed by peptide affinity purification

Immunogen: KLH conjugated synthetic peptide between 100-128 amino acids from the N-terminal region of Human GALNT4

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.25 mg/mL

Buffer: PBS containing 0.09 % (W/V) Sodium Azide as preservative

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Details zu GALNT4

Target: GALNT4 (UDP-N-Acetyl-alpha-D-Galactosamine:polypeptide N-Acetylgalactosaminyltransferase 4 (GalNAc-T4) (GALNT4))

Andere Bezeichnung: GALNT4

Hintergrund: This gene encodes a member of the UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase (GalNAc-T) family of enzymes. GalNAc-Ts initiate mucin-type O-linked glycosylation in the Golgi apparatus by catalyzing the transfer of GalNAc to serine and threonine residues on target proteins. They are characterized by an N-terminal transmembrane domain, a stem region, a lumenal catalytic domain containing a GT1 motif and Gal/GalNAc transferase motif, and a C-terminal ricin/lectin-like domain. GalNAc-Ts have different, but overlapping, substrate specificities and patterns of expression. In vitro, the encoded protein can complement other GalNAc-Ts in the complete O-glycosylation of the mucin-1 tandem repeat and can O-glycosylate the P-selectin glycoprotein ligand-1 Molecule. The coding region of this gene is contained within a single exon.Synonyms: GalNAc transferase 4, GalNAc-T4, Polypeptide N-acetylgalactosaminyltransferase 4, Protein-UDP acetylgalactosaminyltransferase 4, UDP-GalNAc:polypeptide N-acetylgalactosaminyltransferase 4, pp-GaNTase 4

Molekulargewicht: 66608 Da

Gen-ID: 8693

NCBI Accession: NP_003765