Fukutin Antikörper (Middle Region)
Kurzübersicht für Fukutin Antikörper (Middle Region) (ABIN952403)
Target
Alle Fukutin (FKTN) Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- AA 184-214, Middle Region
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Spezifität
- This antibody recognizes Human and Mouse FKTN (Center).
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Aufreinigung
- Protein A column, followed by peptide affinity purification
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Immunogen
- KLH conjugated synthetic peptide between 184-214 amino acids from the Central region of Human Fukutin. Genename: FKTN
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Isotyp
- Ig Fraction
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Applikationshinweise
- Optimal working dilution should be determined by the investigator.
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- 0.25 mg/mL
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Buffer
- PBS containing 0.09 % (W/V) Sodium Azide as preservative
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Handhabung
- Avoid repeated freezing and thawing.
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Lagerung
- 4 °C/-20 °C
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Informationen zur Lagerung
- Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- Fukutin (FKTN)
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Andere Bezeichnung
- Fukutin
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Hintergrund
- The protein encoded by this gene is a putative transmembrane protein that is localized to the cis-Golgi compartment, where it may be involved in the glycosylation of alpha-dystroglycan in skeletal muscle. The encoded protein is thought to be a glycosyltransferase and could play a role in brain development. Defects in this gene are a cause of Fukuyama-type congenital muscular dystrophy (FCMD), Walker-Warburg syndrome (WWS), limb-girdle muscular dystrophy type 2M (LGMD2M), and dilated cardiomyopathy type 1X (CMD1X). Alternatively spliced transcript variants have been found for this gene.Synonyms: FCMD, FKTN, Fukuyama-type congenital muscular dystrophy protein
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Molekulargewicht
- 53724 Da
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Gen-ID
- 2218
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NCBI Accession
- NP_001073270
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Pathways
- Regulation of Carbohydrate Metabolic Process
Target
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