FOLR2 Antikörper (N-Term)

Produktnummer ABIN952352

Der Kaninchen Polyklonal anti-FOLR2 Antikörper wird verwendet zum Nachweis von FOLR2 in Proben von Human. Er wurde validiert für WB und EIA.

Kurzübersicht für FOLR2 Antikörper (N-Term) (ABIN952352)

Target: FOLR2 (Folate Receptor 2 (Fetal) (FOLR2))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser FOLR2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Enzyme Immunoassay (EIA)

Produktdetails anti-FOLR2 Antikörper

Bindungsspezifität: AA 16-44, N-Term

Spezifität: This antibody recognizes Human Folate receptor beta (N-term).

Aufreinigung: Protein A column, followed by peptide affinity purification

Immunogen: KLH conjugated synthetic peptide between 16-44 amino acids from the N-terminal region of Human Folate receptor beta Genename: FOLR2

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.25 mg/mL

Buffer: PBS containing 0.09 % (W/V) Sodium Azide as preservative

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Details zu FOLR2

Target: FOLR2 (Folate Receptor 2 (Fetal) (FOLR2))

Andere Bezeichnung: Folate Receptor beta

Hintergrund: The protein encoded by this gene is a member of the folate receptor (FOLR) family, and these genes exist in a cluster on chromosome 11. Members of this gene family have a high affinity for folic acid and for several reduced folic acid derivatives, and they mediate delivery of 5-methyltetrahydrofolate to the interior of cells. This protein has a 68 % and 79 % sequence homology with the FOLR1 and FOLR3 proteins, respectively. Although this protein was originally thought to be specific to placenta, it can also exist in other tissues, and it may play a role in the transport of methotrexate in synovial macrophages in rheumatoid arthritis patients. Multiple transcript variants that encode the same protein have been found for this gene.Synonyms: FOLR2, FR-beta, Folate receptor 2, Placental folate-binding protein

Molekulargewicht: 29280 Da

Gen-ID: 2350

NCBI Accession: NP_001107008

Pathways: Dicarboxylic Acid Transport