FEZF1 Antikörper (N-Term)

Produktnummer ABIN952301

Der Kaninchen Polyklonal anti-FEZF1 Antikörper wird verwendet zum Nachweis von FEZF1 in Proben von Human und Maus. Er wurde validiert für WB und EIA.

Kurzübersicht für FEZF1 Antikörper (N-Term) (ABIN952301)

Target: FEZF1 (FEZ Family Zinc Finger 1 (FEZF1))

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser FEZF1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Enzyme Immunoassay (EIA)

Produktdetails anti-FEZF1 Antikörper

Bindungsspezifität: AA 67-96, N-Term

Spezifität: This antibody reacts to FEZF1.

Kreuzreaktivität (Details): Species reactivity (tested):Human and Mouse.

Aufreinigung: Affinity chromatography on Protein A

Immunogen: KLH conjugated synthetic peptide between 67-96 amino acids from the N-terminal region of human FEZF1

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.25 mg/mL

Buffer: PBS, 0.09 % (W/V) sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Details zu FEZF1

Target: FEZF1 (FEZ Family Zinc Finger 1 (FEZF1))

Andere Bezeichnung: FEZF1

Hintergrund: Transcription repressor. Involved in the axonal projection and proper termination of olfactory sensory neurons (OSN). Plays a role in rostro-caudal patterning of the diencephalon and in prethalamic formation. Expression is required in OSN to cell-autonomously regulate OSN axon projections. Regulates non-cell-autonomously the layer formation of the olfactory bulb development and the interneurons. May be required for correct rostral migration of the interneuron progenitors. FEZF1 is expressed in brain. Little or no expression in other tissues. Overexpressed specifically in gastric cancers. A 2-to 20-fold increase is found in over 50 % of gastric cancer tissues. Subcellular location of FEZF1 is in the nucleus.Synonyms: FEZ, Fez family zinc finger protein 1, ZNF312B, Zinc finger protein 312B

Molekulargewicht: 52038 Da

Gen-ID: 389549

NCBI Accession: NP_001019784