FBXO4 Antikörper (Middle Region)

Produktnummer ABIN952288

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch FBXO4 in WB und EIA. Er zeigt eine Reaktivität gegenüber Human und wurde in 1 Publikation erwähnt.

Kurzübersicht für FBXO4 Antikörper (Middle Region) (ABIN952288)

Target: FBXO4 (F-Box Protein 4 (FBXO4))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser FBXO4 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Enzyme Immunoassay (EIA)

Produktdetails anti-FBXO4 Antikörper

Bindungsspezifität: AA 231-260, Middle Region

Spezifität: This antibody recognizes Human FBXO4 (Center).

Aufreinigung: Affinity Chromatography on Protein A

Immunogen: KLH conjugated synthetic peptide between 231~260 amino acids from the Center region of human FBXO4

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.25 mg/mL

Buffer: PBS containing 0.09 % (W/V) Sodium Azide as preservative

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Referenzen für anti-FBXO4 Antikörper (ABIN952288)

Barbash, Zamfirova, Lin, Chen, Yang, Nakagawa, Lu, Rustgi, Diehl: "Mutations in Fbx4 inhibit dimerization of the SCF(Fbx4) ligase and contribute to cyclin D1 overexpression in human cancer." in: Cancer cell, Vol. 14, Issue 1, pp. 68-78, (2008) (PubMed).

Details zu FBXO4

Target: FBXO4 (F-Box Protein 4 (FBXO4))

Andere Bezeichnung: FBXO4

Hintergrund: FBXO4 encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of the ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein belongs to the Fbxs class.Synonyms: F-box only protein 4, FBX4

Molekulargewicht: 44136 Da

Gen-ID: 26272

NCBI Accession: NP_036308