Der Kaninchen Polyklonal Anti-ETFA Antikörper wurde für WB, FACS, IHC (p) und EIA validiert. Er ist geeignet, ETFA in Proben von Human und Maus zu detektieren.
ETFA participates in catalyzing the initial step of the mitochondrial fatty acid beta-oxidation. It shuttles electrons between primary flavoprotein dehydrogenases and the membrane-bound electron transfer flavoprotein ubiquinone oxidoreductase. Defects in electron-transfer-flavoprotein have been implicated in type II glutaricaciduria in which multiple acyl-CoA dehydrogenase deficiencies result in large excretion of glutaric, lactic, ethylmalonic, butyric, isobutyric, 2-methyl-butyric, and isovaleric acids. Two transcript variants encoding different isoforms have been found for this gene.Synonyms: Alpha-ETF, Electron transfer flavoprotein subunit alpha