Endothelin 1 Antikörper (Middle Region)

Produktnummer ABIN952083

Dieses Anti-Endothelin 1-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von Endothelin 1 in WB, IF, IHC (p), FACS und EIA. Geeignet für Human.

Kurzübersicht für Endothelin 1 Antikörper (Middle Region) (ABIN952083)

Target: Endothelin 1 (EDN1)

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Endothelin 1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Flow Cytometry (FACS), Enzyme Immunoassay (EIA)

Produktdetails anti-Endothelin 1 Antikörper

Bindungsspezifität: AA 118-146, Middle Region

Spezifität: This antibody recognizes Human Endothelin-1 (Center).

Aufreinigung: Affinity Chromatography on Protein A

Immunogen: KLH conjugated synthetic peptide between 118-146 amino acids from the Central region of human EDN1

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.25 mg/mL

Buffer: PBS containing 0.09 % (W/V) Sodium Azide as preservative

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Details zu Endothelin 1

Target: Endothelin 1 (EDN1)

Andere Bezeichnung: Endothelin-1

Hintergrund: The protein encoded by this gene is proteolytically processed to release a secreted peptide termed endothelin 1. This peptide is a potent vasoconstrictor and is produced by vascular endothelial cells. Endothelin 1 also can affect the central nervous system. Two transcript variants encoding different isoforms have been found for this gene.Synonyms: EDN1, ET1, HDLCQ7, PPET1, Preproendothelin-1

Molekulargewicht: 24425 Da

Gen-ID: 1906

NCBI Accession: NP_001161791

Pathways: Hormone Transport, Negative Regulation of Hormone Secretion, Regulation of Systemic Arterial Blood Pressure by Hormones, cAMP Metabolic Process, Regulation of Muscle Cell Differentiation, Regulation of G-Protein Coupled Receptor Protein Signaling, Regulation of Cell Size