Emilin1 Antikörper

Produktnummer ABIN952077

Dieses Anti-Emilin1-Antikörper ist ein Ratte Monoklonal-Antikörper zur Detektion von Emilin1 in WB, IHC (fro) und IF. Geeignet für Maus.

Kurzübersicht für Emilin1 Antikörper (ABIN952077)

Target: Emilin1 (EMILIN1) (Elastin Microfibril Interfacer 1 (EMILIN1))

Reaktivität: Maus

Wirt: Ratte

Klonalität: Monoklonal

Konjugat: Dieser Emilin1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunofluorescence (IF)

Klon: C11A8

Produktdetails anti-Emilin1 Antikörper

Spezifität: This antibody was selected for its ability to detect Murine Emilin-1.

Kreuzreaktivität (Details): Species reactivity (tested):Mouse.

Aufreinigung: Affinity Chromatography on Protein G

Immunogen: Recombinant Mouse Emilin-1

Isotyp: IgG2a

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Rekonstitution: Restore in sterile water to a concentration is 0.1-1.0 mg/mL. Centrifuge vial prior to opening.

Buffer: PBS

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Prior to reconstitution store at 2-8 °C for one month or at -20 °C for longer. Following reconstitution store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Details zu Emilin1

Target: Emilin1 (EMILIN1) (Elastin Microfibril Interfacer 1 (EMILIN1))

Andere Bezeichnung: EMILIN1

Hintergrund: Emilin-1 is an extracellular matrix glycoprotein localized at sites where elastin and microfibrils are in proximity. It may be responsible for anchoring smooth muscle cells to elastic fibers. It has cell adhesive capacity. Emilin-1 may have a role in the regulation of blood vessel assembly since it inhibits TGFB signaling by binding specifically to the pro-TGFB precursor and preventing its maturation by furin convertases in the extracellular space. TGFB proteins are the main regulators of blood vessel development and maintenance.Synonyms: EMI, EMILIN-1, Elastin microfibril interface-located protein 1, Elastin microfibril interfacer 1

Gen-ID: 100952

NCBI Accession: NP_598679

UniProt: Q99K41