Der Kaninchen Polyklonal Anti-DUSP2-Antikörper wurde für WB, FACS und EIA validiert. Er ist geeignet, DUSP2 in Proben von Human und Maus zu detektieren.
DUSP2
Reaktivität: Human
IF (cc), IF (p)
Wirt: Kaninchen
Polyclonal
AbBy Fluor® 647
Applikationshinweise
Optimal working dilution should be determined by the investigator.
Beschränkungen
Nur für Forschungszwecke einsetzbar
Format
Liquid
Konzentration
0.25 mg/mL
Buffer
PBS containing 0.09 % (W/V) Sodium Azide as preservative
Konservierungsmittel
Sodium azide
Vorsichtsmaßnahmen
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handhabung
Avoid repeated freezing and thawing.
Lagerung
4 °C/-20 °C
Informationen zur Lagerung
Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
Target
DUSP2
(Dual Specificity Phosphatase 2 (DUSP2))
Andere Bezeichnung
DUSP2 / PAC1
Hintergrund
DUSP2 is a member of the dual specificity protein phosphatase subfamily. These phosphatases inactivate their target kinases by dephosphorylating both the phosphoserine/threonine and phosphotyrosine residues. They negatively regulate members of the mitogen-activated protein (MAP) kinase superfamily (MAPK/ERK, SAPK/JNK, p38), which are associated with cellular proliferation and differentiation. Different members of the family of dual specificity phosphatases show distinct substrate specificities for various MAP kinases, different tissue distribution and subcellular localization, and different modes of inducibility of their expression by extracellular stimuli.Synonyms: Dual specificity protein phosphatase 2, Dual specificity protein phosphatase PAC-1, PAC-1