CSDA Antikörper (Middle Region)

Produktnummer ABIN951934

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch CSDA in WB und EIA. Er zeigt eine Reaktivität gegenüber Human und Maus und wurde in 6+ Publikationen erwähnt.

Kurzübersicht für CSDA Antikörper (Middle Region) (ABIN951934)

Target: CSDA (Cold Shock Domain Protein A (CSDA))

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CSDA Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Enzyme Immunoassay (EIA)

Produktdetails anti-CSDA Antikörper

Bindungsspezifität: AA 151-181, Middle Region

Spezifität: This antibody recognizes Human and Mouse DNA-binding protein A (Center).

Aufreinigung: Affinity Chromatography on Protein A

Immunogen: KLH conjugated synthetic peptide between 151-181 amino acids from the Central region of Human CSDA. Genename: CSDA

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.25 mg/mL

Buffer: PBS, 0.09 % Sodium Azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Referenzen für anti-CSDA Antikörper (ABIN951934)

Lima, Parreira, Devuyst, Caplanusi, Nkuli, Marien, Van Der Smissen, Alves, Verroust, Christensen, Terzi, Matter, Balda, Pierreux, Courtoy: "ZONAB promotes proliferation and represses differentiation of proximal tubule epithelial cells." in: Journal of the American Society of Nephrology : JASN, Vol. 21, Issue 3, pp. 478-88, (2010) (PubMed).

Gao, Kang, Liao, Ding, Gambotto, Watkins, Liu, Stolz, Yin: "Biochemical isolation and characterization of the tubulovesicular LC3-positive autophagosomal compartment." in: The Journal of biological chemistry, Vol. 285, Issue 2, pp. 1371-83, (2010) (PubMed).

Buchert, Darido, Lagerqvist, Sedello, Cazevieille, Buchholz, Bourgaux, Pannequin, Joubert, Hollande: "The symplekin/ZONAB complex inhibits intestinal cell differentiation by the repression of AML1/Runx1." in: Gastroenterology, Vol. 137, Issue 1, pp. 156-64, 164.e1-3, (2009) (PubMed).

Sharpe Elles, Sykes, Williamson, Uhlenbeck: "A dominant negative mutant of the E. coli RNA helicase DbpA blocks assembly of the 50S ribosomal subunit." in: Nucleic acids research, Vol. 37, Issue 19, pp. 6503-14, (2009) (PubMed).

Wang, Zheng, Che, Wang, Zhao, Wu, Zeng, Pan, He: "Upregulation of human DNA binding protein A (dbpA) in gastric cancer cells." in: Acta pharmacologica Sinica, Vol. 30, Issue 10, pp. 1436-42, (2009) (PubMed).

Hayashi, Kajino, Umeda, Takano, Arakawa, Kudo, Hino: "Somatic mutation and SNP in the promoter of dbpA and human hepatocarcinogenesis." in: International journal of oncology, Vol. 21, Issue 4, pp. 847-50, (2002) (PubMed).

Details zu CSDA

Target: CSDA (Cold Shock Domain Protein A (CSDA))

Andere Bezeichnung: DNA-Binding Protein A

Hintergrund: CSDA binds to the GM-CSF promoter. Seems to act as a repressor. Binds also to full length mRNA and to short RNA sequences containing the consensus site 5'-UCCAUCA-3'. May have a role in translation repression (By similarity).Synonyms: CSDA, CSDA1, Cold shock domain-containing protein A, DBPA, Single-strand DNA-binding protein NF-GMB, ZONAB

Molekulargewicht: 40090 Da

Gen-ID: 8531

NCBI Accession: NP_001138898

Pathways: Negative Regulation of intrinsic apoptotic Signaling