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DLL3 Antikörper (C-Term)

DLL3 Reaktivität: Human WB, IF, IHC (p), EIA Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN951924
  • Target Alle DLL3 Antikörper anzeigen
    DLL3 (delta Like Protein 3 (DLL3))
    Bindungsspezifität
    • 10
    • 7
    • 6
    • 6
    • 5
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 526-556, C-Term
    Reaktivität
    • 52
    • 24
    • 5
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    Human
    Wirt
    • 53
    • 2
    Kaninchen
    Klonalität
    • 53
    • 2
    Polyklonal
    Konjugat
    • 22
    • 6
    • 5
    • 5
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser DLL3 Antikörper ist unkonjugiert
    Applikation
    • 50
    • 27
    • 21
    • 18
    • 10
    • 2
    • 2
    • 2
    Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)
    Spezifität
    This antibody recognizes DLL3 at C-term .
    Kreuzreaktivität (Details)
    Species reactivity (tested):Human
    Aufreinigung
    Purified through a Protein A column followed by peptide affinity purification
    Immunogen
    Synthetic peptide - KLH conjugated - corresponding to the C-terminal region (between 526-556aa) of human DLL3.
    Isotyp
    Ig Fraction
    Top Product
    Discover our top product DLL3 Primärantikörper
  • Applikationshinweise
    Optimal working dilution should be determined by the investigator.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    0.25 mg/mL
    Buffer
    PBS with 0.09 % (W/V) Sodium azide
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handhabung
    Avoid repeated freezing and thawing.
    Lagerung
    4 °C/-20 °C
    Informationen zur Lagerung
    Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • Target
    DLL3 (delta Like Protein 3 (DLL3))
    Andere Bezeichnung
    DLL3 (DLL3 Produkte)
    Synonyme
    SCDO1 antikoerper, pu antikoerper, pudgy antikoerper, delta like canonical Notch ligand 3 antikoerper, delta-like 3 (Drosophila) antikoerper, DLL3 antikoerper, Dll3 antikoerper
    Hintergrund
    Delta-like protein 3 is a ligand for the Notch signaling pathway. It inhibits primary neurogenesis. DLL3 plays a role in the formation of somite boundaries during segmentation of the paraxial mesoderm. Defects in DLL3 are the cause of Spondylocostal dysostosis autosomal recessive type 1 (SCDO1). Mutations in DLL3 gene cause truncal shortening relative to their limbs, which leads to abdominal protrusion, abnormal spinal curvature and sometimes a plagiocephaly-torticollis sequence. It may be required to divert neurons along a specific differentiation pathway.Synonyms: Delta-3, Delta-like protein 3
    Gen-ID
    10683
    NCBI Accession
    NP_058637
    Pathways
    Notch Signalweg
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