DIAPH3 Antikörper (C-Term)
Kurzübersicht für DIAPH3 Antikörper (C-Term) (ABIN951910)
Target
Alle DIAPH3 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- AA 1060-1090, C-Term
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Spezifität
- This antibody recognizes Human DIAPH3 (C-term).
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Aufreinigung
- Affinity Chromatography on Protein A
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Immunogen
- KLH conjugated synthetic peptide between 1060-1090 amino acids from the C-terminal region of human DIAPH3.
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Isotyp
- Ig Fraction
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Applikationshinweise
- Optimal working dilution should be determined by the investigator.
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- 0.25 mg/mL
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Buffer
- PBS, 0.09 % Sodium Azide
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Handhabung
- Avoid repeated freezing and thawing.
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Lagerung
- 4 °C/-20 °C
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Informationen zur Lagerung
- Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- DIAPH3 (Diaphanous Homolog 3 (Drosophila) (DIAPH3))
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Andere Bezeichnung
- DIAPH3
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Hintergrund
- DIAPH3 binds to GTP-bound form of Rho and to profilin. Acts in a Rho-dependent manner to recruit profilin to the membrane, where it promotes actin polymerization. It is required for cytokinesis, stress fiber formation, and transcriptional activation of the serum response factor. DFR proteins couple Rho and Src tyrosine kinase during signaling and the regulation of actin dynamics (By similarity).Synonyms: DIAP3, DRF3, Diaphanous homolog 3, Diaphanous-3, Diaphanous-related formin-3
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Molekulargewicht
- 136926 Da
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Gen-ID
- 81624
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NCBI Accession
- NP_001035982
Target
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