Complex IV Subunit VIb (AA 58-86), (C-Term) Antikörper

Produktnummer ABIN951654

Dieses Anti--Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von in EIA, IHC (p) und WB. Geeignet für Human.

Kurzübersicht für Complex IV Subunit VIb (AA 58-86), (C-Term) Antikörper (ABIN951654)

Target: Complex IV Subunit VIb

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Applikation: Enzyme Immunoassay (EIA), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)

Produktdetails

Bindungsspezifität: AA 58-86, C-Term

Spezifität: This antibody reacts to COX6B1.

Kreuzreaktivität (Details): Species reactivity (tested):Human.

Aufreinigung: Affinity chromatography on Protein A

Immunogen: KLH conjugated synthetic peptide between 58-86 amino acids from the C-terminal region of human COX6B1

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.25 mg/mL

Buffer: PBS, 0.09 % (W/V) sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Antigendetails

Target: Complex IV Subunit VIb

Hintergrund: Cytochrome c oxidase (COX), the terminal enzyme of the mitochondrial respiratory chain, catalyzes the electron transfer from reduced cytochrome c to oxygen. It is a heteromeric complex consisting of 3 catalytic subunits encoded by mitochondrial genes and multiple structural subunits encoded by nuclear genes. The mitochondrially-encoded subunits function in electron transfer, and the nuclear-encoded subunits may be involved in the regulation and assembly of the complex. This nuclear gene encodes subunit VIb. Mutations in this gene are associated with severe infantile encephalomyopathy. Three pseudogenes COX6BP-1, COX6BP-2 and COX6BP-3 have been found on chromosomes 7, 17 and 22q13.1-13.2, respectively.Synonyms: COX6B, COX6B1, Cytochrome c oxidase subunit 6B1, Mitochondria Complex IV

Molekulargewicht: 10192 Da

Gen-ID: 1340

NCBI Accession: NP_001854