Coilin Antikörper (Middle Region)
Kurzübersicht für Coilin Antikörper (Middle Region) (ABIN951619)
Target
Alle Coilin (COIL) Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- AA 156-186, Middle Region
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Spezifität
- This antibody reacts to COIL.
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Kreuzreaktivität (Details)
- Species reactivity (tested):Human.
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Aufreinigung
- Affinity chromatography on Protein A
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Immunogen
- KLH conjugated synthetic peptide between 156-186 amino acids from the Central region of human COIL
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Isotyp
- Ig Fraction
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Applikationshinweise
- Optimal working dilution should be determined by the investigator.
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- 0.25 mg/mL
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Buffer
- PBS, 0.09 % (W/V) sodium azide
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Handhabung
- Avoid repeated freezing and thawing.
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Lagerung
- 4 °C/-20 °C
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Informationen zur Lagerung
- Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- Coilin (COIL)
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Andere Bezeichnung
- Coilin
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Hintergrund
- The protein encoded by this gene is an integral component of Cajal bodies (also called coiled bodies). Cajal bodies are nuclear suborganelles of varying number and composition that are involved in the post-transcriptional modification of small nuclear and small nucleolar RNAs. The N-terminus of the coilin protein directs its self-oligomerization while the C-terminus influences the number of nuclear bodies assembled per cell. Differential methylation and phosphorylation of coilin likely influences its localization among nuclear bodies and the composition and assembly of Cajal bodies. This gene has pseudogenes on chromosome 4 and chromosome 14.Synonyms: CLN80, COIL, p80
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Molekulargewicht
- 62608 Da
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Gen-ID
- 8161
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NCBI Accession
- NP_004636
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Pathways
- Ribonucleoprotein Complex Subunit Organization
Target
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