Factor VII Antikörper

Produktnummer ABIN951602

Es gibt 1 Publikation für dieses Produkt. Der Maus Monoklonal anti-Factor VII Antikörper wird verwendet zum Nachweis von Factor VII in Proben von Human. Er wurde validiert für WB und EIA.

Kurzübersicht für Factor VII Antikörper (ABIN951602)

Target: Factor VII (F7) (Coagulation Factor VII (F7))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser Factor VII Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Enzyme Immunoassay (EIA)

Klon: AA-3

Produktdetails anti-Factor VII Antikörper

Spezifität: This antibody is specific for factor VII/VIIa (AA-3).

Kreuzreaktivität (Details): Also reacts to: VIIa

Aufreinigung: Affinity chromatography on Protein G

Immunogen: Human Factor VII (AA-3) purified from plasma.

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1,0 mg/mL

Buffer: PBS containing 0.02 % sodium azide (NaN3) as preservative

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Referenzen für anti-Factor VII Antikörper (ABIN951602)

Schut, Kirschbaum, Adelmeijer, de Groot, Lisman: "In vitro uptake of recombinant factor VIIa by megakaryocytes with subsequent production of platelets containing functionally active drug." in: British journal of haematology, (2016) (PubMed).

Details zu Factor VII

Target: Factor VII (F7) (Coagulation Factor VII (F7))

Hintergrund: Human blood coagulation factor VII is a 50 kD, vitamin K dependent, plasma glycoprotein synthesized in the liver and secreted into the blood as a single chain zymogen of serine protease factor VIIa. Factor VII participates in a cascade of reactions leading to the coagulation of blood and contains two Epidermal Growth Factor (EGF) domains. This antibody recognizes an epitope in the first EGF-like domain of factor VII/VIIa. Factor VII participates in the extrinsic pathway of blood coagulation in an Activated form called factor VIIa. Factor VII can be converted to VIIa by Factor IXa or thrombin.Synonyms: Proconvertin, SPCA, Serum prothrombin conversion accelerator

Gen-ID: 2155

NCBI Accession: NP_000122

UniProt: P08709

Pathways: Response to Growth Hormone Stimulus, Platelet-derived growth Factor Receptor Signaling