Coagulation Factor IX Antikörper

Produktnummer ABIN951595

Dieser Schaf Polyklonal Antikörper detektiert spezifisch Coagulation Factor IX in IHC (p), EIA und ID. Es zeigt Reaktivität gegenüber Proben von Human.

Kurzübersicht für Coagulation Factor IX Antikörper (ABIN951595)

Target: Coagulation Factor IX (F9)

Reaktivität: Human

Wirt: Schaf

Klonalität: Polyklonal

Konjugat: Dieser Coagulation Factor IX Antikörper ist unkonjugiert

Applikation: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA), Immunodiffusion (ID)

Produktdetails anti-Coagulation Factor IX Antikörper

Spezifität: Recognizes Human Factor IX as demonstrated by Immunodiffusion. A single positive reactivity band was observed with Normal Human Plasma. No reaction was observed against Factor IX-deficient plasma.

Kreuzreaktivität (Details): Species reactivity (tested):Human.

Aufreinigung: Ammonium Sulfate Precipitation

Immunogen: Human Factor IX purified from plasma.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 10 mg/mL

Buffer: 0.01 M HEPES, pH 7.4, 0.1 M Sodium Chloride and 50 % Glycerol.

Konservierungsmittel: Azide free

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Details zu Coagulation Factor IX

Target: Coagulation Factor IX (F9)

Hintergrund: Coagulation Factor IX (F9) circulates in the blood as an inactive zymogen. This factor is converted to an active form by factor XIa, which excises the activation peptide and thus generates a heavy chain and a light chain held together by one or more disulfide bonds. The role of this activated factor IX in the blood coagulation cascade is to activate factor X to its active form through interactions with Ca+2 ions, membrane phospholipids, and factor VIII. Alterations of this gene, including point mutations, insertions and deletions, cause factor IX deficiency, which is a recessive X-linked disorder, also called hemophilia B or Christmas disease.Synonyms: Christmas factor, PTC, Plasma thromboplastin component

Gen-ID: 2158

NCBI Accession: NP_000124