Coagulation Factor IX Antikörper
Kurzübersicht für Coagulation Factor IX Antikörper (ABIN951594)
Target
Alle Coagulation Factor IX (F9) Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
Klon
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Spezifität
- Recognises Factor IX
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Aufreinigung
- Protein G Chromatography
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Immunogen
- Full length native protein (purified) (Human).
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Isotyp
- IgG1
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Applikationshinweise
- Optimal working dilution should be determined by the investigator.
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Konzentration
- 3.5 mg/mL
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Buffer
- 0.05 M Sodium Phosphate, 0.5 M NaCl, 1 mM EDTA, pH 6.6
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Handhabung
- Avoid repeated freezing and thawing.
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Lagerung
- -80 °C
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Informationen zur Lagerung
- Store at -70 °C.
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- Coagulation Factor IX (F9)
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Hintergrund
- Coagulation Factor IX (F9) circulates in the blood as an inactive zymogen. This factor is converted to an active form by factor XIa, which excises the activation peptide and thus generates a heavy chain and a light chain held together by one or more disulfide bonds. The role of this activated factor IX in the blood coagulation cascade is to activate factor X to its active form through interactions with Ca+2 ions, membrane phospholipids, and factor VIII. Alterations of this gene, including point mutations, insertions and deletions, cause factor IX deficiency, which is a recessive X-linked disorder, also called hemophilia B or Christmas disease.Synonyms: Christmas factor, PTC, Plasma thromboplastin component
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Gen-ID
- 2158
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NCBI Accession
- NP_000124
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UniProt
- P00740
Target
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