Dieses Anti-Coagulation Factor IX-Antikörper ist ein Maus Monoklonal-Antikörper zur Detektion von Coagulation Factor IX in WB, IHC (p) und EIA. Geeignet für Human.
F9
Reaktivität: Human
WB, ELISA
Wirt: Kaninchen
Polyclonal
unconjugated
Applikationshinweise
Optimal working dilution should be determined by the investigator.
Beschränkungen
Nur für Forschungszwecke einsetzbar
Konzentration
3.5 mg/mL
Buffer
0.05 M Sodium Phosphate, 0.5 M NaCl, 1 mM EDTA, pH 6.6
Handhabung
Avoid repeated freezing and thawing.
Lagerung
-80 °C
Informationen zur Lagerung
Store at -70 °C.
Target
Coagulation Factor IX (F9)
Hintergrund
Coagulation Factor IX (F9) circulates in the blood as an inactive zymogen. This factor is converted to an active form by factor XIa, which excises the activation peptide and thus generates a heavy chain and a light chain held together by one or more disulfide bonds. The role of this activated factor IX in the blood coagulation cascade is to activate factor X to its active form through interactions with Ca+2 ions, membrane phospholipids, and factor VIII. Alterations of this gene, including point mutations, insertions and deletions, cause factor IX deficiency, which is a recessive X-linked disorder, also called hemophilia B or Christmas disease.Synonyms: Christmas factor, PTC, Plasma thromboplastin component