Claudin 6 Antikörper (Middle Region)

Produktnummer ABIN951551

Der Kaninchen Polyklonal anti-Claudin 6 Antikörper wird verwendet zum Nachweis von Claudin 6 in Proben von Human und Maus. Er wurde validiert für WB und EIA.

Kurzübersicht für Claudin 6 Antikörper (Middle Region) (ABIN951551)

Target: Claudin 6 (CLDN6)

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Claudin 6 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Enzyme Immunoassay (EIA)

Produktdetails anti-Claudin 6 Antikörper

Bindungsspezifität: AA 133-163, Middle Region

Spezifität: This antibody recognizes Human CLDN6. Other species not tested.

Aufreinigung: Protein A column, followed by peptide affinity purification

Immunogen: KLH conjugated synthetic peptide between 133-163 amino acids from the Central region of human CLDN6

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.25 mg/mL

Buffer: PBS, 0.09 % (W/V) Sodium Azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Details zu Claudin 6

Target: Claudin 6 (CLDN6)

Andere Bezeichnung: Claudin-6 / CLDN6

Hintergrund: Tight junctions represent one mode of cell-to-cell adhesion in epithelial or endothelial cell sheets, forming continuous seals around cells and serving as a physical barrier to prevent solutes and water from passing freely through the paracellular space. These junctions are comprised of sets of continuous networking strands in the outwardly facing cytoplasmic leaflet, with complementary grooves in the inwardly facing extracytoplasmic leaflet. This gene encodes a component of tight junction strands, which is a member of the claudin family. The protein is an integral membrane protein and is one of the entry cofactors for hepatitis C virus. The gene methylation may be involved in esophageal tumorigenesis. This gene is adjacent to another family member CLDN9 on chromosome 16.Synonyms: PRO1488, Skullin, Skullin 2, UNQ757

Molekulargewicht: 23292 Da

Gen-ID: 9074

NCBI Accession: NP_067018

Pathways: Hepatitis C