CHADL Antikörper (Middle Region)

Produktnummer ABIN951491

Der Kaninchen Polyklonal Anti-CHADL-Antikörper wurde für WB und EIA validiert. Er ist geeignet, CHADL in Proben von Human zu detektieren.

Kurzübersicht für CHADL Antikörper (Middle Region) (ABIN951491)

Target: CHADL (Chondroadherin-Like (CHADL))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CHADL Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Enzyme Immunoassay (EIA)

Produktdetails anti-CHADL Antikörper

Bindungsspezifität: AA 405-434, Middle Region

Spezifität: This antibody reacts to CHADL.

Kreuzreaktivität (Details): Species reactivity (tested):Human.

Aufreinigung: Affinity chromatography on Protein A

Immunogen: KLH conjugated synthetic peptide between 405-434 amino acids from the Central region of human CHADL

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.25 mg/mL

Buffer: PBS, 0.09 % (W/V) sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Details zu CHADL

Target: CHADL (Chondroadherin-Like (CHADL))

Andere Bezeichnung: CHADL

Hintergrund: Members of the small leucine-rich proteoglycan (SLRP) family are mostly extracellular proteins that function upstream of multiple signaling cascades. They affect intracellular phosphorylation and modulate distinct pathways, such as those driven by Toll-like receptors, TGF? and receptor tyrosine kinases. As a member of the SLRP family, CHADL (Chondroadherin-like protein) is a 762 amino acid protein containing 21 LRR (leucine-rich) repeats, which promote protein-ligand interactions. Chondroadherin, a closely related protein, promotes attachment of chrondocytes, osteoblasts and fibroblasts and also plays an important role in the regulation of chrodrocyte proliferation and growth. CHADL is a secreted protein that is located in the extracellular space. There are two isoforms of CHADL that exist as a result of alternative splicing events.Synonyms: Chondroadherin-like protein, SLRR4B

Molekulargewicht: Isoform2 74kd. 82388 Da

Gen-ID: 150356

NCBI Accession: NP_612490