CEBPA Antikörper (C-Term)
Kurzübersicht für CEBPA Antikörper (C-Term) (ABIN951460)
Target
Alle CEBPA Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- AA 310-339, C-Term
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Spezifität
- This antibody reacts to CEBPA.
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Kreuzreaktivität (Details)
- Species reactivity (tested):Human and Mouse.
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Aufreinigung
- Affinity chromatography on Protein A
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Immunogen
- KLH conjugated synthetic peptide between 310~339 amino acids from the C-terminal region of human CEBPA
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Isotyp
- Ig Fraction
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Applikationshinweise
- Optimal working dilution should be determined by the investigator.
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- 0.25 mg/mL
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Buffer
- PBS, 0.09 % (W/V) sodium azide
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Handhabung
- Avoid repeated freezing and thawing.
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Lagerung
- 4 °C/-20 °C
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Informationen zur Lagerung
- Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- CEBPA (CCAAT/enhancer Binding Protein (C/EBP), alpha (CEBPA))
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Andere Bezeichnung
- CEBPA
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Hintergrund
- CEBPA is a bZIP transcription factor which can bind as a homodimer to certain promoters and enhancers. It can also form heterodimers with the related proteins CEBP-beta and CEBP-gamma. This protein has been shown to bind to the promoter and modulate the expression of the gene encoding leptin, a protein that plays an important role in body weight homeostasis. Also, the protein can interact with CDK2 and CDK4, thereby inhibiting these kinases and causing growth arrest in cultured cells.Synonyms: C/EBP alpha, CCAAT/enhancer-binding protein alpha
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Molekulargewicht
- 37561 Da
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Gen-ID
- 1050
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NCBI Accession
- NP_004355
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Pathways
- Brown Fat Cell Differentiation, Positive Regulation of fat Cell Differentiation
Target
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