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CD99 Antikörper

CD99 Reaktivität: Human FACS Wirt: Maus Monoclonal 3B2-TA8 unconjugated

Produktnummer ABIN951444

Datenblatt (PDF)

Target Alle CD99 Antikörper anzeigen

CD99
Reaktivität
101

24

9

6

1
Human
Wirt
73

48

4
Maus
Passende Sekundärantikörper
Klonalität
70

55
Monoklonal
Konjugat
52

11

10

7

3

2

2

2

2

2

2

2

2

2

2

2

2

2

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1
Dieser CD99 Antikörper ist unkonjugiert
Applikation
60

53

32

29

23

18

14

13

13

12

6

5

4

1

1
Flow Cytometry (FACS)

Spezifität

This antibody recognizes CD99, an approximately 32 kDa sialoglycoprotein expressed on many cell types, with particularly strong expression on Ewing´s sarcoma and peripheral primitive neuroectodermal tumors. Within the hematopoietic system, CD99 is expressed on virtually all cell types except granulocytes.

Kreuzreaktivität (Details)

Species reactivity (tested):Human

Aufreinigung

Protein-A affinity chromatography

Immunogen

Human thymocytes

Klon

3B2-TA8

Isotyp

IgG2a

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Applikationshinweise

Optimal working dilution should be determined by the investigator.

Beschränkungen

Nur für Forschungszwecke einsetzbar
Konzentration

1.0 mg/mL (> 95% pure by SDS-PAGE)

Buffer

Phosphate buffered saline (PBS) with 15 mM sodium azide, approx. pH 7.4

Konservierungsmittel

Sodium azide

Vorsichtsmaßnahmen

This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung

Avoid repeated freezing and thawing.

Lagerung

4 °C/-20 °C

Informationen zur Lagerung

Store the antibody at 2 - 8 °C up to one month or (in aliquots) at -20 °C for longer.
Target

CD99

Andere Bezeichnung

CD99 / MIC2 (CD99 Produkte)

Substanzklasse

Viral Protein

Hintergrund

CD99 is a ubiquitous transmembrane type I sialoglycoprotein of a unique and poorly characterized protein family. CD99 is heavily O-glycosylated and was described as a T cell costimulator and strong activator of integrin-mediated actin cytoskeleton assembly, promoting cell adhesion and homotypic aggregation, immediate arrest on an inflamed vascular endothelium, and cell migration through it. Ligation of CD99 under some conditions can lead to apoptosis. Originally CD99 was described as a human thymus leukemia antigen, an Ewing´s sarcoma-specific membrane marker, and an adhesion molecule involved in spontaneous rosette formation of T cells with erythrocytes.Synonyms: 12E7, E2 antigen, MIC2X, MIC2Y, Protein MIC2, T-cell surface glycoprotein E2

Gen-ID

4267

NCBI Accession

NP_001116370

UniProt

P14209