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Integrin beta 3 Antikörper
ITGB3
Reaktivität: Human, Primate
WB, FACS, IHC (fro)
Wirt: Maus
Monoclonal
VIPL2
unconjugated
Produktdetails anti-Integrin beta 3 Antikörper
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Target
Alle Integrin beta 3 (ITGB3) Antikörper anzeigen
Integrin beta 3 (ITGB3)
Reaktivität
Alle Reaktivitäten für Integrin beta 3 Antikörper
Human, Primate
Wirt
Alle Wirte für Integrin beta 3 Antikörper
Maus
Klonalität
Alle Klonalitäten für Integrin beta 3 Antikörper
Monoklonal
Konjugat
Alle Konjugate für Integrin beta 3 Antikörper
Dieser Integrin beta 3 Antikörper ist unkonjugiert
Applikation
Alle Applikationen für Integrin beta 3 Antikörper
Western Blotting (WB), Flow Cytometry (FACS), Immunohistochemistry (Frozen Sections) (IHC (fro))
Spezifität
This antibody detects CD61, a 90-110 kDa transmembrane glycoprotein of integrin family, expressed on platelets, megacaryocytes, osteoclasts, endothelial cells and other cell types, including leucocytes and smooth muscle cells.
Kreuzreaktivität (Details)
Species reactivity (tested):Human, Non-Human Primates
Aufreinigung
Protein-A affinity chromatography
Reinheit
> 95 % pure by SDS-PAGE
Klon
VIPL2
Isotyp
IgG1
Top Product
Discover our top product ITGB3 Primärantikörper
Alternativen
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Anwendungsinformationen
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Applikationshinweise
Optimal working dilution should be determined by the investigator.
Beschränkungen
Nur für Forschungszwecke einsetzbar
Handhabung
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Konzentration
1.0 mg/mL
Buffer
Phosphate buffered saline (PBS) with 15 mM sodium azide, approx. pH 7.4
Konservierungsmittel
Sodium azide
Vorsichtsmaßnahmen
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handhabung
Avoid repeated freezing and thawing.
Lagerung
4 °C/-20 °C
Informationen zur Lagerung
Store the antibody at 2 - 8 °C up to one month or (in aliquots) at -20 °C for longer.
Details zu Integrin beta 3
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Target
Integrin beta 3 (ITGB3)
Andere Bezeichnung
CD61 / ITGB3 (ITGB3 Produkte )
Synonyme
BDPLT16 antikoerper, BDPLT2 antikoerper, CD61 antikoerper, GP3A antikoerper, GPIIIa antikoerper, GT antikoerper, INGRB3 antikoerper, integrin antikoerper, INTB3 antikoerper, GPIIIA antikoerper, cd61 antikoerper, gp3a antikoerper, itgb3 antikoerper, itgb3.2 antikoerper, itgb3.1 antikoerper, integrin subunit beta 3 antikoerper, integrin beta 3 antikoerper, integrin subunit beta 3 L homeolog antikoerper, integrin beta 3a antikoerper, integrin beta 3b antikoerper, ITGB3 antikoerper, Itgb3 antikoerper, itgb3.L antikoerper, itgb3a antikoerper, itgb3b antikoerper
Hintergrund
CD61 (beta3 integrin) is a transmembrane glycoprotein, which associates with CD41 or CD51 Molecules to form heterodimeric adhesion receptores. CD41/CD61 complex is one of the earliest markers of the megakaryocytic lineage. It binds to fibronectin, fibrinogen and von Willebrand factor, and is involved in platelet aggregation. CD51/CD61 complex has similar binding properties and is involved in modulating migration and survival of angiogenic endothelial cells.Synonyms: GP3A, GPIIIa, Integrin beta-3, Platelet membrane glycoprotein IIIa
Gen-ID
3690
NCBI Accession
NP_000203
UniProt
P05106
Pathways
Regulation of G-Protein Coupled Receptor Protein Signaling , Signaling Events mediated by VEGFR1 and VEGFR2 , Smooth Muscle Cell Migration , Integrin Complex
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