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Integrin beta 3 Antikörper

ITGB3 Reaktivität: Human, Primate WB, FACS, IHC (fro) Wirt: Maus Monoclonal VIPL2 unconjugated
Produktnummer ABIN951364
  • Target Alle Integrin beta 3 (ITGB3) Antikörper anzeigen
    Integrin beta 3 (ITGB3)
    Reaktivität
    • 183
    • 99
    • 68
    • 17
    • 15
    • 13
    • 12
    • 9
    • 8
    • 8
    • 5
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Human, Primate
    Wirt
    • 120
    • 67
    • 16
    • 2
    • 2
    Maus
    Klonalität
    • 115
    • 90
    Monoklonal
    Konjugat
    • 107
    • 16
    • 12
    • 11
    • 8
    • 4
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser Integrin beta 3 Antikörper ist unkonjugiert
    Applikation
    • 124
    • 94
    • 54
    • 46
    • 31
    • 30
    • 24
    • 20
    • 15
    • 13
    • 13
    • 5
    • 5
    • 5
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Flow Cytometry (FACS), Immunohistochemistry (Frozen Sections) (IHC (fro))
    Spezifität
    This antibody detects CD61, a 90-110 kDa transmembrane glycoprotein of integrin family, expressed on platelets, megacaryocytes, osteoclasts, endothelial cells and other cell types, including leucocytes and smooth muscle cells.
    Kreuzreaktivität (Details)
    Species reactivity (tested):Human, Non-Human Primates
    Aufreinigung
    Protein-A affinity chromatography
    Reinheit
    > 95 % pure by SDS-PAGE
    Klon
    VIPL2
    Isotyp
    IgG1
    Top Product
    Discover our top product ITGB3 Primärantikörper
  • Applikationshinweise
    Optimal working dilution should be determined by the investigator.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Konzentration
    1.0 mg/mL
    Buffer
    Phosphate buffered saline (PBS) with 15 mM sodium azide, approx. pH 7.4
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handhabung
    Avoid repeated freezing and thawing.
    Lagerung
    4 °C/-20 °C
    Informationen zur Lagerung
    Store the antibody at 2 - 8 °C up to one month or (in aliquots) at -20 °C for longer.
  • Target
    Integrin beta 3 (ITGB3)
    Andere Bezeichnung
    CD61 / ITGB3 (ITGB3 Produkte)
    Hintergrund
    CD61 (beta3 integrin) is a transmembrane glycoprotein, which associates with CD41 or CD51 Molecules to form heterodimeric adhesion receptores. CD41/CD61 complex is one of the earliest markers of the megakaryocytic lineage. It binds to fibronectin, fibrinogen and von Willebrand factor, and is involved in platelet aggregation. CD51/CD61 complex has similar binding properties and is involved in modulating migration and survival of angiogenic endothelial cells.Synonyms: GP3A, GPIIIa, Integrin beta-3, Platelet membrane glycoprotein IIIa
    Gen-ID
    3690
    NCBI Accession
    NP_000203
    UniProt
    P05106
    Pathways
    Regulation of G-Protein Coupled Receptor Protein Signaling, Signaling Events mediated by VEGFR1 and VEGFR2, Smooth Muscle Cell Migration, Integrin Complex
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