IGSF8 Antikörper (Middle Region)

Produktnummer ABIN951296

Der Kaninchen Polyklonal Anti-IGSF8-Antikörper wurde für WB, IHC (p) und EIA validiert. Er ist geeignet, IGSF8 in Proben von Human und Maus zu detektieren.

Kurzübersicht für IGSF8 Antikörper (Middle Region) (ABIN951296)

Target: IGSF8 (Immunoglobulin Superfamily, Member 8 (IGSF8))

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser IGSF8 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Produktdetails anti-IGSF8 Antikörper

Bindungsspezifität: AA 233-262, Middle Region

Spezifität: This antibody detects IGSF8 (Center).

Kreuzreaktivität (Details): Species reactivity (tested):Human, Mouse

Aufreinigung: Purified through a protein A column; followed by peptide affinity purification.

Immunogen: Synthetic peptide (233-262 aa) - KLH conjugated - corresponding to internal domain of human IGSF8.

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.25 mg/mL

Buffer: PBS with 0.09 % (W/V) Sodium Azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Details zu IGSF8

Target: IGSF8 (Immunoglobulin Superfamily, Member 8 (IGSF8))

Andere Bezeichnung: CD316 / IGSF8

Hintergrund: GSF8/PGRL/EWI-2 is a membrane protein that contains 4 Ig domains and forms highly proximal, specific and stoichiometric complexes with both CD9 and CD81 a tetraspanin. Tetraspanins and their molecular partners from primary complexes that then undergo tetraspanin-tetraspanin interactions to form a network of molecular interactions call a tetraspanin web. IGSF8 then may play a key role in diverse functions ascribed to CD81 and CD9 including oocyte fertilization or hepatitis C virus function, regulation of proliferation and differentiation of keratinocytes. It may also be a negative regulator of cell motility and suppress T-cell mobility coordinately with CD81.Synonyms: CD81 partner 3, CD81P3, EWI2, Glu-Trp-Ile EWI motif-containing protein 2, Immunoglobulin superfamily member 8, KCT4, Keratinocytes-associated transmembrane protein 4, LIR-D1

Gen-ID: 93185

NCBI Accession: NP_001193594