IGSF8 Antikörper (Middle Region)

Produktnummer ABIN951296

Der Kaninchen Polyklonal anti-IGSF8 Antikörper wird verwendet zum Nachweis von IGSF8 in Proben von Human und Maus. Er wurde validiert für WB, IHC (p) und EIA.

Kurzübersicht für IGSF8 Antikörper (Middle Region) (ABIN951296)

Target: IGSF8 (Immunoglobulin Superfamily, Member 8 (IGSF8))

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser IGSF8 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Produktdetails anti-IGSF8 Antikörper

Bindungsspezifität: AA 233-262, Middle Region

Spezifität: This antibody detects IGSF8 (Center).

Kreuzreaktivität (Details): Species reactivity (tested):Human, Mouse

Aufreinigung: Purified through a protein A column; followed by peptide affinity purification.

Immunogen: Synthetic peptide (233-262 aa) - KLH conjugated - corresponding to internal domain of human IGSF8.

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.25 mg/mL

Buffer: PBS with 0.09 % (W/V) Sodium Azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Details zu IGSF8

Target: IGSF8 (Immunoglobulin Superfamily, Member 8 (IGSF8))

Andere Bezeichnung: CD316 / IGSF8

Hintergrund: GSF8/PGRL/EWI-2 is a membrane protein that contains 4 Ig domains and forms highly proximal, specific and stoichiometric complexes with both CD9 and CD81 a tetraspanin. Tetraspanins and their molecular partners from primary complexes that then undergo tetraspanin-tetraspanin interactions to form a network of molecular interactions call a tetraspanin web. IGSF8 then may play a key role in diverse functions ascribed to CD81 and CD9 including oocyte fertilization or hepatitis C virus function, regulation of proliferation and differentiation of keratinocytes. It may also be a negative regulator of cell motility and suppress T-cell mobility coordinately with CD81.Synonyms: CD81 partner 3, CD81P3, EWI2, Glu-Trp-Ile EWI motif-containing protein 2, Immunoglobulin superfamily member 8, KCT4, Keratinocytes-associated transmembrane protein 4, LIR-D1

Gen-ID: 93185

NCBI Accession: NP_001193594