This antibody recognises Mouse CD200R, a cell surface glycoprotein (OX2R). In mouse CD200R is expressed primarily by peripheral blood monocytes and neutrophils but also by other leucocytes including T-lymphocytes and mast cells. (1) Studies suggest that CD200-CD200R interaction may be involved in the control of myeloid cellular function.
Aufreinigung
Purified IgG prepared by affinity chromatography on Protein G from tissue culture supernatant
Optimal working dilution should be determined by the investigator.
Beschränkungen
Nur für Forschungszwecke einsetzbar
Konzentration
0.1 mg/mL
Buffer
PBS, pH 7.4 containing 0.09 % Sodium Azide as preservative and 1 % BSA as stabilizer.
Konservierungsmittel
Sodium azide
Vorsichtsmaßnahmen
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handhabung
Avoid repeated freezing and thawing. This product is photosensitive and should be protected from light.
Lagerung
4 °C/-20 °C
Informationen zur Lagerung
Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
Target
CD200R1
(CD200 Receptor 1 (CD200R1))
Andere Bezeichnung
CD200R
Hintergrund
A cell surface glycoprotein (also known as OX2R). In humans and mice CD200R is expressed primarily by peripheral blood monocytes and neutrophils but also by other leukocytes including T lymphocytes and mast cells. Studies suggest that CD200-CD200R interaction may be involved in the control of myeloid cellular function. Levels of expression on resting peripheral blood cells are relatively low. CD200R interacts with Human herpesvirus 8 (HHV8 or KSV) vOX2 protein.Synonyms: CD200 Receptor 1, CD200 cell surface glycoprotein receptor, CD200R1, CRTR2, Cell surface glycoprotein CD200 receptor 1, Cell surface glycoprotein OX2 receptor 1, MOX2R, OX2R