BST1 Antikörper

Produktnummer ABIN951197

Der Ratte Monoklonal Anti-BST1 Antikörper wurde für FACS validiert. Er ist geeignet, BST1 in Proben von Maus zu detektieren.

Kurzübersicht für BST1 Antikörper (ABIN951197)

Target: BST1 (Bone Marrow Stromal Cell Antigen 1 (BST1))

Reaktivität: Maus

Wirt: Ratte

Klonalität: Monoklonal

Konjugat: Dieser BST1 Antikörper ist unkonjugiert

Applikation: Flow Cytometry (FACS)

Klon: KT157

Produktdetails anti-BST1 Antikörper

Spezifität: This Monoclonal Antibody reacts with Mouse CD157.

Aufreinigung: Protein G Chromatography

Immunogen: T cell hybridoma J774. Donor: Balb/c mouse spleen cells. Fusion Partner: NSO Mouse Myelom a Partner.

Isotyp: IgG2c

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1.0 mg/mL

Buffer: PBS containing 0.02 % Sodium Azide as preservative

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Details zu BST1

Target: BST1 (Bone Marrow Stromal Cell Antigen 1 (BST1))

Andere Bezeichnung: CD157 / BST1

Hintergrund: CD157 also known as BP-3 Alloantigen or Bone marrow Stromal cell antigen-1 (BST-1), is a 38-48 KDa differentially glycosylated glycosylphosphatidylinositol (GPI) anchored cell surface glycoprotein. CD157, like CD38 belongs to a family of genetically related pleiotropic ectoenzymes. The CD157 antigen is expressed on thymocytes, bone marrow B cells, neutrophils, macrophages, stromal cells, intestinal epithelial cells, the collecting tubules of the kidney and reticular cells in lymph nodes. The CD157 receptor has ADP ribosyl cyclase and cyclic ADP ribose hydrolase biochemical activities. Studies show CD157 is a receptor that induces reorganization of the cytoskeleton and significant changes in cell shape. CD157 is also a mediator of neutrophil adhesion and migration. Signals mediated by CD157 act through modulation of cytosolic [Ca2+]. CD157 is also involved in cellular adhesion to the extracellular matrix.Synonyms: ADP-ribosyl cyclase 2, BST-1, Bone marrow stromal antigen 1, Cyclic ADP-ribose hydrolase 2, cADPr hydrolase 2

Gen-ID: 12182

NCBI Accession: NP_033893

UniProt: Q64277