SLAMF1 Antikörper

Produktnummer ABIN951192

Dieser Anti-SLAMF1 Antikörper ist ein Maus Monoklonal Antikörper zur Detektion von SLAMF1 in FACS, IP und IF. Geeignet für Human.

Kurzübersicht für SLAMF1 Antikörper (ABIN951192)

Target: SLAMF1 (Signaling Lymphocytic Activation Molecule Family Member 1 (SLAMF1))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser SLAMF1 Antikörper ist unkonjugiert

Applikation: Flow Cytometry (FACS), Immunoprecipitation (IP), Immunofluorescence (IF)

Klon: SLAM-4

Produktdetails anti-SLAMF1 Antikörper

Spezifität: This Monoclonal SLAM.4 antibody recognizes CD150, a cell surface molecule expressed on lymphocytes and involved in their activation.

Kreuzreaktivität (Details): Species reactivity (tested):Human.

Aufreinigung: Protein A-affinity chromatography

Immunogen: Human CD150-transfected 300.19 cells

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1.0 mg/mL (> 95% pure by SDS-PAGE)

Buffer: Azide free phosphate buffered saline (PBS), pH ~7.4, 0.2 μm filter sterilized

Konservierungsmittel: Azide free

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store the antibody at 2 - 8 °C up to one month or (in aliquots) at -20 °C for longer.

Details zu SLAMF1

Target: SLAMF1 (Signaling Lymphocytic Activation Molecule Family Member 1 (SLAMF1))

Andere Bezeichnung: CD150 / SLAMF1

Hintergrund: CD150, also known as SLAM (signaling lymphocyte activation molecule) is a 70-95 kDa single chain transmembrane phosphoglycoprotein of the CD2 family. Its extracellular part contains eight potential N-glycosylation sites, and the intracellular tail contains three unique tyrosine-based motifs. These binding sites can be recognized by SH2-binding phosphatases and the adaptor proteins, such as SAP/SH2D1A or EAT-2. The SLAM family receptors are involved in leucocyte activation and contribute to the effective germinal center formation, generation of high-affinity antibody-secreting plasma cells, and memory T and B cells, thereby facilitating long-term immune response. CD150 expression is upregulated after cell activation.Synonyms: CDw150, Ipo-3, Signaling lymphocytic activation molecule, Slam

Gen-ID: 6504

NCBI Accession: NP_003028

UniProt: Q13291