CBX8 Antikörper (Middle Region)
Kurzübersicht für CBX8 Antikörper (Middle Region) (ABIN951075)
Target
Alle CBX8 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- AA 160-189, Middle Region
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Spezifität
- This antibody reacts to CBX8.
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Kreuzreaktivität (Details)
- Species reactivity (tested):Mouse.
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Aufreinigung
- Affinity chromatography on Protein A
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Immunogen
- KLH conjugated synthetic peptide between 160-189 amino acids from the Central region of human CBX8
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Isotyp
- Ig Fraction
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Applikationshinweise
- Optimal working dilution should be determined by the investigator.
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- 0.25 mg/mL
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Buffer
- PBS, 0.09 % (W/V) sodium azide
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Handhabung
- Avoid repeated freezing and thawing.
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Lagerung
- 4 °C/-20 °C
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Informationen zur Lagerung
- Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- CBX8 (Chromobox Homolog 8 (CBX8))
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Andere Bezeichnung
- CBX8
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Hintergrund
- Component of the Polycomb group (PcG) multiprotein PRC1 complex, a complex required to maintain the transcriptionally repressive state of many genes, including Hox genes, throughout development. PcG PRC1 complex acts via chromatin remodeling and modification of histones, it mediates monoubiquitination of histone H2A 'Lys-119', rendering chromatin heritably changed in its expressibility.Synonyms: Chromobox protein homolog 8, PC3, Polycomb 3 homolog, RC1, Rectachrome 1
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Molekulargewicht
- 43396 Da
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Gen-ID
- 57332
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NCBI Accession
- NP_065700
Target
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