GDF5 Antikörper (C-Term)

Produktnummer ABIN950667

Der Kaninchen Polyklonal anti-GDF5 Antikörper (ABIN950667) detektiert spezifisch GDF5 in WB, IHC (p) und EIA. Dieser Antikörper reagiert spezifisch mit Proben aus Human.

Kurzübersicht für GDF5 Antikörper (C-Term) (ABIN950667)

Target: GDF5 (Growth Differentiation Factor 5 (GDF5))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser GDF5 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Produktdetails anti-GDF5 Antikörper

Bindungsspezifität: AA 350-379, C-Term

Spezifität: This antibody recognizes Human BMP14 / GDF5 (C-term).

Aufreinigung: Protein A column, followed by peptide affinity purification

Immunogen: conjugated synthetic peptide between 350-379 amino acids from the C-terminal region of human BMP14 / GDF5

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.25 mg/mL

Buffer: PBS containing 0.09 % (W/V) Sodium Azide as preservative

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Details zu GDF5

Target: GDF5 (Growth Differentiation Factor 5 (GDF5))

Andere Bezeichnung: BMP14 / GDF5

Hintergrund: The protein encoded by this gene is a member of the bone morphogenetic protein (BMP) family and the TGF-beta superfamily. This group of proteins is characterized by a polybasic proteolytic processing site which is cleaved to produce a mature protein containing seven conserved cysteine residues. The members of this family are regulators of cell growth and differentiation in both embryonic and adult tissues. Mutations in this gene are associated with acromesomelic dysplasia, Hunter-Thompson type, brachydactyly, type C, and chondrodysplasia, Grebe type. These associations confirm that the gene product plays a role in skeletal development.Synonyms: Bone Morphogenetic Protein 14, CDMP1, Cartilage-derived morphogenetic protein 1, GDF-5, Growth/differentiation factor 5, Radotermin

Molekulargewicht: 55411 Da

Gen-ID: 8200

NCBI Accession: NP_000548