Azurocidin Antikörper (Middle Region)

Produktnummer ABIN950583

Dieses Anti-Azurocidin-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von Azurocidin in WB und EIA. Geeignet für Human.

Kurzübersicht für Azurocidin Antikörper (Middle Region) (ABIN950583)

Target: Azurocidin (AZU1) (Azurocidin 1 (AZU1))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Azurocidin Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Enzyme Immunoassay (EIA)

Produktdetails anti-Azurocidin Antikörper

Bindungsspezifität: AA 66-96, Middle Region

Spezifität: This antibody reacts to Azurocidin.

Kreuzreaktivität (Details): Species reactivity (tested):Human.

Aufreinigung: Affinity chromatography on Protein A

Immunogen: KLH conjugated synthetic peptide between 66-96 amino acids from the Central region of human AZU1

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.25 mg/mL

Buffer: PBS containing 0.09 % (W/V) sodium azide as preservative

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Details zu Azurocidin

Target: Azurocidin (AZU1) (Azurocidin 1 (AZU1))

Andere Bezeichnung: Azurocidin

Hintergrund: Azurophil granules, specialized lysosomes of the neutrophil, contain at least 10 proteins implicated in the killing of microorganisms. The protein encoded by this gene is an azurophil granule antibiotic protein, with monocyte chemotactic and antibacterial activity. It is also an important multifunctional inflammatory mediator. This encoded protein is a member of the serine protease gene family but it is not a serine proteinase, because the active site serine and histidine residues are replaced. The genes encoding this protein, neutrophil elastase 2, and proteinase 3 are in a cluster located at chromosome 19pter. All 3 genes are expressed coordinately and their protein products are packaged together into azurophil granules during neutrophil differentiation.Synonyms: CAP37, Cationic antimicrobial protein CAP37, HBP, Heparin-binding protein

Gen-ID: 566

NCBI Accession: NP_001691