ANGPTL4 Antikörper (Middle Region)

Produktnummer ABIN950414

Der Kaninchen Polyklonal anti-ANGPTL4 Antikörper wird verwendet zum Nachweis von ANGPTL4 in Proben von Human und Maus. Er wurde validiert für WB, IHC (p) und EIA.

Kurzübersicht für ANGPTL4 Antikörper (Middle Region) (ABIN950414)

Target: ANGPTL4 (Angiopoietin-Like 4 (ANGPTL4))

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser ANGPTL4 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Produktdetails anti-ANGPTL4 Antikörper

Bindungsspezifität: AA 145-175, Middle Region

Spezifität: This antibody reacts to ANGPTL4.

Kreuzreaktivität (Details): Species reactivity (tested):Human and Mouse.

Aufreinigung: Saturated Ammonium Sulfate (SAS) precipitation

Immunogen: KLH conjugated synthetic peptide between 145~175 amino acids from the Center region of human ANGPTL4

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.25 mg/mL

Buffer: PBS containing 0.09 % (W/V) sodium azide as preservative

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Details zu ANGPTL4

Target: ANGPTL4 (Angiopoietin-Like 4 (ANGPTL4))

Andere Bezeichnung: ANGPTL4 / FIAF

Hintergrund: ANGPTL4 is a member of the angiopoietin/angiopoietin-like gene family and encodes a glycosylated, secreted protein with a fibrinogen C-terminal domain. This protein is induced under hypoxic conditions in endothelial cells and is the target of peroxisome proliferation activators. The encoded protein is a serum hormone directly involved in regulating glucose homeostasis, lipid metabolism, and insulin sensitivity and also acts as an apoptosis survival factor for vascular endothelial cells. The encoded protein may play a role in several cancers and it also has been shown to prevent the metastatic process by inhibiting vascular activity as well as tumor cell motility and invasiveness. Decreased expression of this protein has been associated with type 2 diabetes.Synonyms: ARP4, Angiopoietin-like 4, Angiopoietin-related protein 4, Fasting-induced adipose factor, HFARP, Hepatic fibrinogen/angiopoietin-related protein, PGAR

Gen-ID: 51129

NCBI Accession: NP_001034756

Pathways: Regulation of Lipid Metabolism by PPARalpha