ALX4 Antikörper (Middle Region)
Kurzübersicht für ALX4 Antikörper (Middle Region) (ABIN950384)
Target
Alle ALX4 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- AA 256-283, Middle Region
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Spezifität
- This antibody reacts to ALX4.
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Kreuzreaktivität (Details)
- Species reactivity (tested):Human.
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Aufreinigung
- Affinity chromatography on Protein A
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Immunogen
- KLH conjugated synthetic peptide between 256-283 amino acids from the Central region of human ALX4
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Isotyp
- Ig Fraction
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Applikationshinweise
- Optimal working dilution should be determined by the investigator.
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- 0.25 mg/mL
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Buffer
- PBS containing 0.09 % (W/V) sodium azide as preservative
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Handhabung
- Avoid repeated freezing and thawing.
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Lagerung
- 4 °C/-20 °C
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Informationen zur Lagerung
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- ALX4 (ALX Homeobox 4 (ALX4))
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Andere Bezeichnung
- ALX4
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Hintergrund
- This gene encodes a paired-like homeodomain transcription factor expressed in the mesenchyme of developing bones, limbs, hair, teeth, and mammary tissue. Mutations in this gene cause parietal foramina 2 (PFM2), an autosomal dominant disease characterized by deficient ossification of the parietal bones. Mutations in this gene also cause a form of frontonasal dysplasia with alopecia and hypogonadism, suggesting a role for this gene in craniofacial development, mesenchymal-epithelial communication, and hair follicle development. Deletion of a segment of chromosome 11 containing this gene, del(11)(p11p12), causes Potocki-Shaffer syndrome (PSS), a syndrome characterized by craniofacial anomalies, mental retardation, multiple exostoses, and genital abnormalities in males. In mouse, this gene has been shown to use dual translation initiation sites located 16 codons apart.Synonyms: Homeobox protein aristaless-like 4, KIAA1788
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Gen-ID
- 60529
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NCBI Accession
- NP_068745
Target
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